Abstract
Four cases with classic skin manifestations and histologic evidence of dermatomyositis are presented. No occult malignancies were found. After conventional therapy with corticosteroids, hydroxychloroquine and/or methotrexate proved to be limited by side effects or an inadequate clinical response, a therapeutic trial of mycophenolate mofetil was instituted. This relatively new drug, which inhibits lymphocyte proliferation, was effective [with a mean duration of treatment of 13 months (range 6-20)] at controlling cutaneous disease activity, resulting in a decrease of the steroid dose.
Original language | English (US) |
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Pages (from-to) | 1542-1545 |
Number of pages | 4 |
Journal | Journal of Rheumatology |
Volume | 27 |
Issue number | 6 |
State | Published - Jun 26 2000 |
Keywords
- Dermatomyositis
- Mycophenolate mofetil
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Immunology