Infection a Mycobacterium ulcerans

Translated title of the contribution: Mycobacterium ulcerans infection

Hervé Dega, Olivier Chosidow, Stéphane Barete, Bernard Carbonnelle, Jacques Grosset, Vincent Jarlier

Research output: Contribution to journalReview articlepeer-review

Abstract

Mycobacterium ulcerans infection, or Buruli ulcer, is the third most common mycobacterial disease of the immunocompetent host in the tropical areas. M. ulcerans reservoir is aquatic. Infection occurs in children and young adults. The lesion begins with an indolent subcutaneous nodule, principally located on the limbs, that progressively changes into a deep indolent extensive ulcer. M. ulcerans produces a lipidic necrotic and immunosuppressive toxin, named mycolactone, that causes the clinical lesions. In endemic areas, clinical diagnosis is confirmed by microscopic examination. Spontaneous healing occurs after several months or years, causing retractile scars. Surgical excision and grafting is the treatment of choice. Antibiotic therapy is of limited value.

Translated title of the contributionMycobacterium ulcerans infection
Original languageFrench
Pages (from-to)339-344
Number of pages6
JournalAnnales de Medecine Interne
Volume151
Issue number5
StatePublished - Nov 9 2000

Keywords

  • Mycobacterium ulcerans

ASJC Scopus subject areas

  • Internal Medicine

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