TY - JOUR
T1 - Musculoskeletal Effects of Cancer and Cancer Treatment
AU - Wustrack, Rosanna
AU - Rao, Sandesh S.
AU - Morris, Carol D.
N1 - Publisher Copyright:
© American Academy of Orthopaedic Surgeons.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/8/15
Y1 - 2020/8/15
N2 - Improvements in cancer treatment have led to prolonged survival and increased rates of cure. An estimated 14 million cancer survivors live in the United States. The cornerstones of cancer treatment, including radiation, chemotherapy, and surgery, give rise to a host of chronic health conditions, some of which affect the musculoskeletal system. As survivorship continues to improve, orthopaedic surgeons across all subspecialties will be tasked with managing these complications of treatment. This article reviews orthopaedic health concerns secondary to cancer treatment that are likely to present to orthopaedic surgeons for evaluation, such as osteoporosis, osteonecrosis, secondary malignancies, radiation-associated fractures, exercise tolerance, and perioperative evaluation.
AB - Improvements in cancer treatment have led to prolonged survival and increased rates of cure. An estimated 14 million cancer survivors live in the United States. The cornerstones of cancer treatment, including radiation, chemotherapy, and surgery, give rise to a host of chronic health conditions, some of which affect the musculoskeletal system. As survivorship continues to improve, orthopaedic surgeons across all subspecialties will be tasked with managing these complications of treatment. This article reviews orthopaedic health concerns secondary to cancer treatment that are likely to present to orthopaedic surgeons for evaluation, such as osteoporosis, osteonecrosis, secondary malignancies, radiation-associated fractures, exercise tolerance, and perioperative evaluation.
UR - http://www.scopus.com/inward/record.url?scp=85089301423&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85089301423&partnerID=8YFLogxK
U2 - 10.5435/JAAOS-D-18-00491
DO - 10.5435/JAAOS-D-18-00491
M3 - Review article
C2 - 32769720
AN - SCOPUS:85089301423
VL - 28
SP - E716-E728
JO - The Journal of the American Academy of Orthopaedic Surgeons
JF - The Journal of the American Academy of Orthopaedic Surgeons
SN - 1067-151X
IS - 16
ER -