Mumps vaccine effectiveness in highly immunized populations

Angela Domínguez, Núria Torner, Jesús Castilla, Joan Batalla, Pere Godoy, Marcela Guevara, Dolors Carnicer, Joan Caylà, Cristina Rius, Josep Maria Jansà

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of the study was to investigate effectiveness of mumps MMR component in communities with high MMR coverage. Outbreak-related cases of mumps born between 1995 and 2005 notified to Navarre and Catalonia public health services during the period 2005-2007 were studied. Vaccine effectiveness (VE) and their 95%CI were calculated using the screening method. Of 47 confirmed, 85.1% immunized with at least one dose (1MMR) and 44.9% with two (2MMR). Estimated VE was 85.4% (95%CI: 67.3-93.4) for 1MMR and 88.5% (95%CI: 78.1-93.9) for 2MMR. High 2MMR coverage, improved confirmation techniques and further VE studies with all confirmed cases are needed to prevent further outbreaks.

Original languageEnglish (US)
Pages (from-to)3567-3570
Number of pages4
JournalVaccine
Volume28
Issue number20
DOIs
StatePublished - Apr 30 2010

Keywords

  • Immunization
  • Mumps
  • Vaccine effectiveness

ASJC Scopus subject areas

  • Molecular Medicine
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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