Multistage evaluation of measurement error in a reliability study

Aiyi Liu, Enrique F. Schisterman, Chengqing Wu

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

We introduce sequential testing procedures for the planning and analysis of reliability studies to assess an exposure's measurement error. The designs allow repeated evaluation of reliability of the measurements and stop testing if early evidence shows the measurement error is within the level of tolerance. Methods are developed and critical values tabulated for a number of two-stage designs. The methods are exemplified using an example evaluating the reliability of biomarkers associated with oxidative stress.

Original languageEnglish (US)
Pages (from-to)1190-1196
Number of pages7
JournalBiometrics
Volume62
Issue number4
DOIs
StatePublished - Dec 2006
Externally publishedYes

Keywords

  • Interim analysis
  • Intraclass correlation
  • Measurement error
  • Power and sample size

ASJC Scopus subject areas

  • General Immunology and Microbiology
  • Applied Mathematics
  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences
  • Statistics and Probability

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