Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites

Yoshio Inoue, Kathrina Chua, Rebecca F. McClure, Manuel C. Jimenez, Christopher D. Gocke, Ashraf Z. Badros, Naoko Takebe

Research output: Contribution to journalArticle


A pleural effusion is a rare presenting feature of multiple myeloma and can be a complication of myelomatous ascites as well. An additional unique feature of our case includes the finding of a normal bone marrow at the time of presentation despite the aggressive course of the disease. To the best of our knowledge after an extensive medical literature review, this case is the first one of multiple myeloma presenting with a plasmacytic pleural effusion, a negative bone marrow, and a late complication of plasmacytic ascites. Involvement of serous cavities in myeloma carries a poor prognosis, and there is currently no standard effective treatment regimen.

Original languageEnglish (US)
Pages (from-to)715-718
Number of pages4
JournalLeukemia Research
Issue number6
StatePublished - Jun 2005
Externally publishedYes



  • CD 138
  • Hematopoietic stem cell transplant
  • Plasmacytic ascites
  • Plasmacytic pleural effusion

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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