Multiple introductions of HIV-1 subtype E into the western hemisphere

A. W. Artenstein, A. E. Brown, T. C. VanCott, J. R. Mascola, D. S. Burke, J. Coppola, E. Galbarini, P. Schonbrood, J. K. Carr, E. Sanders-Buell, F. E. McCutchan

Research output: Contribution to journalArticlepeer-review

Abstract

There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America. We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases. These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.

Original languageEnglish (US)
Pages (from-to)1197-1198
Number of pages2
JournalThe Lancet
Volume346
Issue number8984
DOIs
StatePublished - Nov 4 1995
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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