Multiple introductions of HIV-1 subtype E into the western hemisphere

A. W. Artenstein; A. E. Brown; T. C. VanCott; J. R. Mascola; D. S. Burke; J. Coppola; E. Galbarini; P. Schonbrood; J. K. Carr; E. Sanders-Buell; F. E. McCutchan

doi:10.1016/S0140-6736(95)92900-2

Multiple introductions of HIV-1 subtype E into the western hemisphere

A. W. Artenstein, A. E. Brown, T. C. VanCott, J. R. Mascola, D. S. Burke, J. Coppola, E. Galbarini, P. Schonbrood, J. K. Carr, E. Sanders-Buell, F. E. McCutchan

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Abstract

There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America. We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases. These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.

Original language	English (US)
Pages (from-to)	1197-1198
Number of pages	2
Journal	The Lancet
Volume	346
Issue number	8984
DOIs	https://doi.org/10.1016/S0140-6736(95)92900-2
State	Published - Nov 4 1995
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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Cite this

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title = "Multiple introductions of HIV-1 subtype E into the western hemisphere",

abstract = "There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America. We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases. These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.",

author = "Artenstein, {A. W.} and Brown, {A. E.} and VanCott, {T. C.} and Mascola, {J. R.} and Burke, {D. S.} and J. Coppola and E. Galbarini and P. Schonbrood and Carr, {J. K.} and E. Sanders-Buell and McCutchan, {F. E.}",

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doi = "10.1016/S0140-6736(95)92900-2",

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TY - JOUR

T1 - Multiple introductions of HIV-1 subtype E into the western hemisphere

AU - Artenstein, A. W.

AU - Brown, A. E.

AU - VanCott, T. C.

AU - Mascola, J. R.

AU - Burke, D. S.

AU - Coppola, J.

AU - Galbarini, E.

AU - Schonbrood, P.

AU - Carr, J. K.

AU - Sanders-Buell, E.

AU - McCutchan, F. E.

PY - 1995/11/4

Y1 - 1995/11/4

N2 - There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America. We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases. These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.

AB - There are nine recognised genetic subtypes of HIV-1, and the epidemic in Southeast Asia is largely due to subtype E. We have investigated HIV-1 viral subtypes in 11 Uruguayan military personnel, six with infection acquired during a United Nations deployment to Cambodia and five with infection acquired in South America. We found subtype E in five of the six infections acquired in Southeast Asia, and subtype B in all five of the domestically acquired cases. These findings document multiple introductions of HIV-1 subtype E into the western hemisphere and mean that the genetic diversity of the global HIV-1 pandemic must be considered in strategies for epidemic control.

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JO - The Lancet

JF - The Lancet

IS - 8984

ER -

Multiple introductions of HIV-1 subtype E into the western hemisphere

Abstract

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