Multiple biologic markers in the monitoring of treatment for patients with small cell carcinoma of the lung

The use of serial levels of plasma CEA and serum carbohydrates

K. B. Woo, T. P. Waalkes, M. D. Abeloff, David S Ettinger, K. L. McNitt, C. W. Gehrke

Research output: Contribution to journalArticle

Abstract

The monitoring utility of serial patterns of a single marker (carcinoembryonic antigen) level and multiple marker (three carbohydrates-fucose, mannose and galactose) levels in patients with small cell carcinoma of the lung was investigated using a quantitative approach. A serial multiple regression (SMR) model was formulated to assess the disease responses following the first to the tenth course of therapy and resulted in the multiple correlations ranging from 0.183 (NS)-0.706 (P5.0 ng/ml are significantly correlated with the disease course whereas the serial levels

Original languageEnglish (US)
Pages (from-to)1633-1642
Number of pages10
JournalCancer
Volume48
Issue number7
StatePublished - 1981

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Small Cell Lung Carcinoma
Physiologic Monitoring
Biomarkers
Carbohydrates
Fucose
Carcinoembryonic Antigen
Differentiation Antigens
Mannose
Serum
Galactose
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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Multiple biologic markers in the monitoring of treatment for patients with small cell carcinoma of the lung : The use of serial levels of plasma CEA and serum carbohydrates. / Woo, K. B.; Waalkes, T. P.; Abeloff, M. D.; Ettinger, David S; McNitt, K. L.; Gehrke, C. W.

In: Cancer, Vol. 48, No. 7, 1981, p. 1633-1642.

Research output: Contribution to journalArticle

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