Multiphasic enhancement patterns of small renal masses (≤4 cm) on preoperative computed tomography

Utility for distinguishing subtypes of renal cell carcinoma, angiomyolipoma, and oncocytoma

Phillip Martin Pierorazio, Elias S. Hyams, Salina Tsai, Zhaoyong Feng, Bruce Trock, Jeffrey K. Mullins, Pamela Johnson, Elliot K Fishman, Mohamad E Allaf

Research output: Contribution to journalArticle

Abstract

Objective: To analyze the enhancement patterns of small renal masses (SRMs) during 4-phase computed tomography (CT) imaging to predict histology. Methods: One-hundred consecutive patients with SRMs and 4-phase preoperative CT imaging, who underwent extirpative surgery with a pathologic diagnosis of renal cell carcinoma (RCC), angiomyolipoma (AML), or oncocytoma, were identified from a single institution. An expert radiologist, blinded to histologic results, retrospectively recorded tumor size, RENAL (radius, exophytic/endophytic properties of the tumor, nearness of tumor deepest portion to the collecting system or sinus, anterior/posterior descriptor, and the location relative to polar lines) nephrometry score, tumor attenuation, and the renal cortex on all 4 acquisitions (precontrast, corticomedullary, nephrogenic, and delayed density). Results: Pathologic diagnoses included 48 clear-cell RCCs (ccRCCs), 22 papillary RCCs, 10 chromophobe RCCs, 13 oncocytomas, and 7 AMLs. There was no significant difference in median tumor size (P =.8), nephrometry score (P =.98), or anatomic location (P >.2) among histologies. Significant differences were noted in peak enhancement (P

Original languageEnglish (US)
Pages (from-to)1265-1271
Number of pages7
JournalUrology
Volume81
Issue number6
DOIs
StatePublished - Jun 2013

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Oxyphilic Adenoma
Angiomyolipoma
Renal Cell Carcinoma
Tomography
Kidney
Neoplasms
Histology

ASJC Scopus subject areas

  • Urology

Cite this

@article{07feca9b8fb74215b7203690da3a91fd,
title = "Multiphasic enhancement patterns of small renal masses (≤4 cm) on preoperative computed tomography: Utility for distinguishing subtypes of renal cell carcinoma, angiomyolipoma, and oncocytoma",
abstract = "Objective: To analyze the enhancement patterns of small renal masses (SRMs) during 4-phase computed tomography (CT) imaging to predict histology. Methods: One-hundred consecutive patients with SRMs and 4-phase preoperative CT imaging, who underwent extirpative surgery with a pathologic diagnosis of renal cell carcinoma (RCC), angiomyolipoma (AML), or oncocytoma, were identified from a single institution. An expert radiologist, blinded to histologic results, retrospectively recorded tumor size, RENAL (radius, exophytic/endophytic properties of the tumor, nearness of tumor deepest portion to the collecting system or sinus, anterior/posterior descriptor, and the location relative to polar lines) nephrometry score, tumor attenuation, and the renal cortex on all 4 acquisitions (precontrast, corticomedullary, nephrogenic, and delayed density). Results: Pathologic diagnoses included 48 clear-cell RCCs (ccRCCs), 22 papillary RCCs, 10 chromophobe RCCs, 13 oncocytomas, and 7 AMLs. There was no significant difference in median tumor size (P =.8), nephrometry score (P =.98), or anatomic location (P >.2) among histologies. Significant differences were noted in peak enhancement (P",
author = "Pierorazio, {Phillip Martin} and Hyams, {Elias S.} and Salina Tsai and Zhaoyong Feng and Bruce Trock and Mullins, {Jeffrey K.} and Pamela Johnson and Fishman, {Elliot K} and Allaf, {Mohamad E}",
year = "2013",
month = "6",
doi = "10.1016/j.urology.2012.12.049",
language = "English (US)",
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pages = "1265--1271",
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number = "6",

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TY - JOUR

T1 - Multiphasic enhancement patterns of small renal masses (≤4 cm) on preoperative computed tomography

T2 - Utility for distinguishing subtypes of renal cell carcinoma, angiomyolipoma, and oncocytoma

AU - Pierorazio, Phillip Martin

AU - Hyams, Elias S.

AU - Tsai, Salina

AU - Feng, Zhaoyong

AU - Trock, Bruce

AU - Mullins, Jeffrey K.

AU - Johnson, Pamela

AU - Fishman, Elliot K

AU - Allaf, Mohamad E

PY - 2013/6

Y1 - 2013/6

N2 - Objective: To analyze the enhancement patterns of small renal masses (SRMs) during 4-phase computed tomography (CT) imaging to predict histology. Methods: One-hundred consecutive patients with SRMs and 4-phase preoperative CT imaging, who underwent extirpative surgery with a pathologic diagnosis of renal cell carcinoma (RCC), angiomyolipoma (AML), or oncocytoma, were identified from a single institution. An expert radiologist, blinded to histologic results, retrospectively recorded tumor size, RENAL (radius, exophytic/endophytic properties of the tumor, nearness of tumor deepest portion to the collecting system or sinus, anterior/posterior descriptor, and the location relative to polar lines) nephrometry score, tumor attenuation, and the renal cortex on all 4 acquisitions (precontrast, corticomedullary, nephrogenic, and delayed density). Results: Pathologic diagnoses included 48 clear-cell RCCs (ccRCCs), 22 papillary RCCs, 10 chromophobe RCCs, 13 oncocytomas, and 7 AMLs. There was no significant difference in median tumor size (P =.8), nephrometry score (P =.98), or anatomic location (P >.2) among histologies. Significant differences were noted in peak enhancement (P

AB - Objective: To analyze the enhancement patterns of small renal masses (SRMs) during 4-phase computed tomography (CT) imaging to predict histology. Methods: One-hundred consecutive patients with SRMs and 4-phase preoperative CT imaging, who underwent extirpative surgery with a pathologic diagnosis of renal cell carcinoma (RCC), angiomyolipoma (AML), or oncocytoma, were identified from a single institution. An expert radiologist, blinded to histologic results, retrospectively recorded tumor size, RENAL (radius, exophytic/endophytic properties of the tumor, nearness of tumor deepest portion to the collecting system or sinus, anterior/posterior descriptor, and the location relative to polar lines) nephrometry score, tumor attenuation, and the renal cortex on all 4 acquisitions (precontrast, corticomedullary, nephrogenic, and delayed density). Results: Pathologic diagnoses included 48 clear-cell RCCs (ccRCCs), 22 papillary RCCs, 10 chromophobe RCCs, 13 oncocytomas, and 7 AMLs. There was no significant difference in median tumor size (P =.8), nephrometry score (P =.98), or anatomic location (P >.2) among histologies. Significant differences were noted in peak enhancement (P

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