Multiparametric and multinuclear magnetic resonance imaging of human breast cancer

Current applications

Research output: Contribution to journalArticle

Abstract

The exploration of novel imaging methods that have the potential to improve specificity for the identification of malignancy is still critically needed in breast imaging. Changes in physiologic alterations of soft tissue water associated with breast cancer can be visualized by magnetic resonance (MR) imaging. However, it is unlikely that a single MR parameter can characterize the complexity of breast tissue. Techniques such as multiparametric MR imaging, proton magnetic resonance spectroscopic (MRSI) imaging, and 23Na sodium MR imaging when used in combination provide a comprehensive data set with potentially more power to diagnose breast disease than any single measure alone. A combination of MR, MRSI, and 23Na sodium MR parameters may be examined in a single MR imaging examination, potentially resulting in improved specificity for radiologic evaluation of malignancy.

Original languageEnglish (US)
Pages (from-to)543-550
Number of pages8
JournalTechnology in Cancer Research and Treatment
Volume3
Issue number6
StatePublished - Dec 2004

Fingerprint

Magnetic Resonance Imaging
Breast Neoplasms
Magnetic Resonance Spectroscopy
Breast
Sodium
Breast Diseases
Protons
Neoplasms
Water

Keywords

  • NA
  • Breast
  • Cancer
  • Diffusion
  • ISODATA
  • Magnetic Resonance Imaging
  • Neoplasm
  • Proton
  • Sodium MR
  • Spectroscopy

ASJC Scopus subject areas

  • Cancer Research
  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Multiparametric and multinuclear magnetic resonance imaging of human breast cancer: Current applications",
abstract = "The exploration of novel imaging methods that have the potential to improve specificity for the identification of malignancy is still critically needed in breast imaging. Changes in physiologic alterations of soft tissue water associated with breast cancer can be visualized by magnetic resonance (MR) imaging. However, it is unlikely that a single MR parameter can characterize the complexity of breast tissue. Techniques such as multiparametric MR imaging, proton magnetic resonance spectroscopic (MRSI) imaging, and 23Na sodium MR imaging when used in combination provide a comprehensive data set with potentially more power to diagnose breast disease than any single measure alone. A combination of MR, MRSI, and 23Na sodium MR parameters may be examined in a single MR imaging examination, potentially resulting in improved specificity for radiologic evaluation of malignancy.",
keywords = "NA, Breast, Cancer, Diffusion, ISODATA, Magnetic Resonance Imaging, Neoplasm, Proton, Sodium MR, Spectroscopy",
author = "Michael Jacobs and Ronald Ouwerkerk and Wolff, {Antonio C} and Vered Stearns and Bottomley, {Paul A} and Barker, {Peter B} and Pedram Argani and Khouri, {Nagi Fouad} and Davidson, {Nancy E.} and Bhujwalla, {Zaver M} and Bluemke, {David A.}",
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T1 - Multiparametric and multinuclear magnetic resonance imaging of human breast cancer

T2 - Current applications

AU - Jacobs, Michael

AU - Ouwerkerk, Ronald

AU - Wolff, Antonio C

AU - Stearns, Vered

AU - Bottomley, Paul A

AU - Barker, Peter B

AU - Argani, Pedram

AU - Khouri, Nagi Fouad

AU - Davidson, Nancy E.

AU - Bhujwalla, Zaver M

AU - Bluemke, David A.

PY - 2004/12

Y1 - 2004/12

N2 - The exploration of novel imaging methods that have the potential to improve specificity for the identification of malignancy is still critically needed in breast imaging. Changes in physiologic alterations of soft tissue water associated with breast cancer can be visualized by magnetic resonance (MR) imaging. However, it is unlikely that a single MR parameter can characterize the complexity of breast tissue. Techniques such as multiparametric MR imaging, proton magnetic resonance spectroscopic (MRSI) imaging, and 23Na sodium MR imaging when used in combination provide a comprehensive data set with potentially more power to diagnose breast disease than any single measure alone. A combination of MR, MRSI, and 23Na sodium MR parameters may be examined in a single MR imaging examination, potentially resulting in improved specificity for radiologic evaluation of malignancy.

AB - The exploration of novel imaging methods that have the potential to improve specificity for the identification of malignancy is still critically needed in breast imaging. Changes in physiologic alterations of soft tissue water associated with breast cancer can be visualized by magnetic resonance (MR) imaging. However, it is unlikely that a single MR parameter can characterize the complexity of breast tissue. Techniques such as multiparametric MR imaging, proton magnetic resonance spectroscopic (MRSI) imaging, and 23Na sodium MR imaging when used in combination provide a comprehensive data set with potentially more power to diagnose breast disease than any single measure alone. A combination of MR, MRSI, and 23Na sodium MR parameters may be examined in a single MR imaging examination, potentially resulting in improved specificity for radiologic evaluation of malignancy.

KW - NA

KW - Breast

KW - Cancer

KW - Diffusion

KW - ISODATA

KW - Magnetic Resonance Imaging

KW - Neoplasm

KW - Proton

KW - Sodium MR

KW - Spectroscopy

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