Multimodality imaging of pulmonary function in the rodent

Nilesh Mistry, Ming De Lin, Laurence Hedlund, G. Allan Johnson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The high spatial and temporal resolution demands for imaging physiological function in the rodent call for the use of novel ways to combine information from different imaging modalities. This work describes ventilation imaging using hyperpolarized (HP) 3He magnetic resonance imaging (MRI) and perfusion imaging using X-ray digital subtraction angiography (DSA). We illustrate the key steps needed to combine the complementary data from the two modalities to provide qualitative and quantitative information on gas exchange in the lungs. The results indicate that multimodality imaging of pulmonary function in small animals can provide functional information at higher spatial and temporal resolution compared to many traditional imaging techniques.

Original languageEnglish (US)
Title of host publication2006 3rd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro - Proceedings
Pages920-923
Number of pages4
StatePublished - Nov 17 2006
Event2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Arlington, VA, United States
Duration: Apr 6 2006Apr 9 2006

Publication series

Name2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
Volume2006

Other

Other2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro
CountryUnited States
CityArlington, VA
Period4/6/064/9/06

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ASJC Scopus subject areas

  • Engineering(all)

Cite this

Mistry, N., De Lin, M., Hedlund, L., & Johnson, G. A. (2006). Multimodality imaging of pulmonary function in the rodent. In 2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings (pp. 920-923). [162569] (2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings; Vol. 2006).