Multimodality cardiovascular molecular imaging technology

Matthew O'Donnell, Elliot R. McVeigh, H. William Strauss, Atsushi Tanaka, Brett E. Bouma, Guillermo J. Tearney, Michael A. Guttman, Ernest V. Garcia

Research output: Contribution to journalReview articlepeer-review

Abstract

Cardiovascular molecular imaging is a new discipline that integrates scientific advances in both functional imaging and molecular probes to improve our understanding of the molecular basis of the cardiovascular system. These advances are driven by in vivo imaging of molecular processes in animals, usually small animals, and are rapidly moving toward clinical applications. Molecular imaging has the potential to revolutionize the diagnosis and treatment of cardiovascular disease. The 2 key components of all molecular imaging systems are the molecular contrast agents and the imaging system providing spatial and temporal localization of these agents within the body. They must deliver images with the appropriate sensitivity and specificity to drive clinical applications. As work in molecular contrast agents matures and highly sensitive and specific probes are developed, these systems will provide the imaging technologies required for translation into clinical tools. This is the promise of molecular medicine.

Original languageEnglish (US)
Pages (from-to)38S-50S
JournalJournal of Nuclear Medicine
Volume51
Issue numberSUPPL.1
DOIs
StatePublished - 2010

Keywords

  • Cardiovascular
  • Molecular imaging
  • Multidisciplinary approach

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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