Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesion

Heidi E. Kirsch; Jehuda P. Sepkuty; Nathan E. Crone

doi:10.1016/j.yebeh.2004.02.001

Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesion

Heidi E. Kirsch, Jehuda P. Sepkuty, Nathan E. Crone

School of Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The effects of chronic epileptogenic lesions on functional anatomy are under debate. Our recent experience during mapping and resection of a lesion in sensorimotor cortex supports the idea that epileptogenic lesions may prompt development of alternate cortical motor representations. Multimodal mapping may uncover alternate areas of functionality that make surgery feasible even when conventional neuroanatomy suggests otherwise. Newer methods such as electrocorticographic spectral analysis may complement traditional electrical cortical stimulation mapping.

Original language	English (US)
Pages (from-to)	407-410
Number of pages	4
Journal	Epilepsy and Behavior
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.yebeh.2004.02.001
State	Published - Jun 2004

Keywords

Cortical plasticity
Electrocorticographic spectral analysis
Electrocorticography
Epilepsy surgery
Functional mapping
Motor cortex

ASJC Scopus subject areas

Neurology
Clinical Neurology
Behavioral Neuroscience

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10.1016/j.yebeh.2004.02.001

Cite this

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title = "Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesion",

abstract = "The effects of chronic epileptogenic lesions on functional anatomy are under debate. Our recent experience during mapping and resection of a lesion in sensorimotor cortex supports the idea that epileptogenic lesions may prompt development of alternate cortical motor representations. Multimodal mapping may uncover alternate areas of functionality that make surgery feasible even when conventional neuroanatomy suggests otherwise. Newer methods such as electrocorticographic spectral analysis may complement traditional electrical cortical stimulation mapping.",

keywords = "Cortical plasticity, Electrocorticographic spectral analysis, Electrocorticography, Epilepsy surgery, Functional mapping, Motor cortex",

author = "Kirsch, {Heidi E.} and Sepkuty, {Jehuda P.} and Crone, {Nathan E.}",

note = "Funding Information: The authors thank Lauren Moo, M.D., for functional magnetic resonance imaging; Frederick Lenz, M.D., Ph.D., for neurosurgical management; and Lei Hao, Ph.D., for technical assistance. This work was supported in part by the National EpiFellows Foundation (H.E.K.), the Epilepsy Foundation of America/Abbot Laboratories (H.E.K.), and NINDS R01-NS40596 (N.E.C.).",

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doi = "10.1016/j.yebeh.2004.02.001",

language = "English (US)",

volume = "5",

pages = "407--410",

journal = "Epilepsy and Behavior",

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AU - Kirsch, Heidi E.

AU - Sepkuty, Jehuda P.

AU - Crone, Nathan E.

N1 - Funding Information: The authors thank Lauren Moo, M.D., for functional magnetic resonance imaging; Frederick Lenz, M.D., Ph.D., for neurosurgical management; and Lei Hao, Ph.D., for technical assistance. This work was supported in part by the National EpiFellows Foundation (H.E.K.), the Epilepsy Foundation of America/Abbot Laboratories (H.E.K.), and NINDS R01-NS40596 (N.E.C.).

PY - 2004/6

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N2 - The effects of chronic epileptogenic lesions on functional anatomy are under debate. Our recent experience during mapping and resection of a lesion in sensorimotor cortex supports the idea that epileptogenic lesions may prompt development of alternate cortical motor representations. Multimodal mapping may uncover alternate areas of functionality that make surgery feasible even when conventional neuroanatomy suggests otherwise. Newer methods such as electrocorticographic spectral analysis may complement traditional electrical cortical stimulation mapping.

AB - The effects of chronic epileptogenic lesions on functional anatomy are under debate. Our recent experience during mapping and resection of a lesion in sensorimotor cortex supports the idea that epileptogenic lesions may prompt development of alternate cortical motor representations. Multimodal mapping may uncover alternate areas of functionality that make surgery feasible even when conventional neuroanatomy suggests otherwise. Newer methods such as electrocorticographic spectral analysis may complement traditional electrical cortical stimulation mapping.

KW - Cortical plasticity

KW - Electrocorticographic spectral analysis

KW - Electrocorticography

KW - Epilepsy surgery

KW - Functional mapping

KW - Motor cortex

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Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesion

Abstract

Keywords

ASJC Scopus subject areas

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