Abstract
Acute and chronic pain management in children is increasingly characterized by either a multimodal or a preventive analgesia approach, in which smaller doses of opioid and nonopioid analgesics, such as nonsteroidal anti-inflammatory drugs, local anaesthetics, N-methyl-D-aspartate antagonists, α2-adrenergic agonists, and voltage-gated calcium channel α-2 δ-proteins, are combined alone and in combination with opioids to maximize pain control and minimize drug-induced adverse side effects. A multimodal approach uses nonpharmacological complementary and alternative medicine therapies too. These include distraction, guided imagery, hypnosis, relaxation techniques, biofeedback, transcutaneous electrical nerve stimulation, and acupuncture. Using the neurophysiology of pain as a blueprint, the molecular targets and strategies used in multimodal pain management are described. Finally, weight-based dosage guidelines for commonly used opioid and nonopioid analgesics are provided to facilitate therapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 851-857 |
| Number of pages | 7 |
| Journal | European Journal of Anaesthesiology |
| Volume | 27 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 2010 |
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Keywords
- Analgesics
- Anticonvulsants
- Clonidine
- Gabapentin
- Narcotic antagonists
- Non-steroidal antiinflammatory drugs
- Opioid
- Pain
- Pregabalin
- Regional anesthesia techniques
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Multimodal analgesia in children. / Yaster, Myron; Traystman, Richard J.
In: European Journal of Anaesthesiology, Vol. 27, No. 10, 10.2010, p. 851-857.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Multimodal analgesia in children
AU - Yaster, Myron
AU - Traystman, Richard J.
PY - 2010/10
Y1 - 2010/10
N2 - Acute and chronic pain management in children is increasingly characterized by either a multimodal or a preventive analgesia approach, in which smaller doses of opioid and nonopioid analgesics, such as nonsteroidal anti-inflammatory drugs, local anaesthetics, N-methyl-D-aspartate antagonists, α2-adrenergic agonists, and voltage-gated calcium channel α-2 δ-proteins, are combined alone and in combination with opioids to maximize pain control and minimize drug-induced adverse side effects. A multimodal approach uses nonpharmacological complementary and alternative medicine therapies too. These include distraction, guided imagery, hypnosis, relaxation techniques, biofeedback, transcutaneous electrical nerve stimulation, and acupuncture. Using the neurophysiology of pain as a blueprint, the molecular targets and strategies used in multimodal pain management are described. Finally, weight-based dosage guidelines for commonly used opioid and nonopioid analgesics are provided to facilitate therapy.
AB - Acute and chronic pain management in children is increasingly characterized by either a multimodal or a preventive analgesia approach, in which smaller doses of opioid and nonopioid analgesics, such as nonsteroidal anti-inflammatory drugs, local anaesthetics, N-methyl-D-aspartate antagonists, α2-adrenergic agonists, and voltage-gated calcium channel α-2 δ-proteins, are combined alone and in combination with opioids to maximize pain control and minimize drug-induced adverse side effects. A multimodal approach uses nonpharmacological complementary and alternative medicine therapies too. These include distraction, guided imagery, hypnosis, relaxation techniques, biofeedback, transcutaneous electrical nerve stimulation, and acupuncture. Using the neurophysiology of pain as a blueprint, the molecular targets and strategies used in multimodal pain management are described. Finally, weight-based dosage guidelines for commonly used opioid and nonopioid analgesics are provided to facilitate therapy.
KW - Analgesics
KW - Anticonvulsants
KW - Clonidine
KW - Gabapentin
KW - Narcotic antagonists
KW - Non-steroidal antiinflammatory drugs
KW - Opioid
KW - Pain
KW - Pregabalin
KW - Regional anesthesia techniques
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UR - http://www.scopus.com/inward/citedby.url?scp=77956832493&partnerID=8YFLogxK
U2 - 10.1097/EJA.0b013e328338c4af
DO - 10.1097/EJA.0b013e328338c4af
M3 - Article
C2 - 20375902
AN - SCOPUS:77956832493
VL - 27
SP - 851
EP - 857
JO - European Journal of Anaesthesiology
JF - European Journal of Anaesthesiology
SN - 0265-0215
IS - 10
ER -