(Figure Presented) The separate encapsulation of nanoparticles (NPs) and pancreatic islets in an alginate capsule-in-capsule (CIC) structure prevents the nanoparticles being toxic to the cells while housing a high payload of nanoparticles for imaging purposes (see picture). The CIC-encapsulated islets showed an improved insulin secretion over cells encapsulated in single capsules and their transplantation into diabetic mice restored normal glycemia.
|Original language||English (US)|
|Number of pages||5|
|Journal||Angewandte Chemie - International Edition|
|State||Published - Mar 1 2011|
- Cell delivery
- Imaging agents
ASJC Scopus subject areas