Multifocal varicella-zoster virus leukoencephalitis in a patient with AIDS: MR findings

Nafi Aygun, Daniel A. Finelli, Mark S. Rodgers, Roy H. Rhodes

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


We describe a patient with AIDS who presented with an acute encephalitis caused by infection with varicella-zoster virus. The hemorrhagic, necrotizing encephalitis had an unusual MR appearance, with innumerable discrete, small, targetlike lesions in the right cerebral hemisphere, which were coalescent in the posterior temporal, parietal, and occipital regions. Of the several known disease patterns of varicella-zoster viral infection in the CNS, this histopathologic pattern of multifocal leukoencephalitis is rare. It is important to recognize, as effective antiviral drug treatments are available.

Original languageEnglish (US)
Pages (from-to)1897-1899
Number of pages3
JournalAmerican Journal of Neuroradiology
Issue number10
StatePublished - Nov 1998
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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