Multifactor Influences of Shared Decision-Making in Acoustic Neuroma Treatment

Jason C. Nellis, Jeff D. Sharon, Seth E. Pross, Lisa Earnest Ishii, Masaru Ishii, Jacob K. Dey, Howard W. Francis

Research output: Contribution to journalArticle

Abstract

Objective: To identify factors associated with treatment modality selection in acoustic neuromas. Study Design: Prospective observational study. Setting: Tertiary care neurotology clinic. Patients: Data were prospectively collected from patients initially presenting to a tertiary care neurotology clinic between 2013 and 2016. Patients who did not have magnetic resonance imaging (MRI), demographic, psychometric, or audiometric data were excluded from analysis. Intervention: Demographic information, clinical symptoms, tumor characteristics, and psychometric data were collected to determine factors associated with undergoing acoustic neuroma surgical resection using univariate and multiple logistic regression analysis. Main Outcome Measure: The decision to pursue acoustic neuroma surgical resection versus active surveillance. Results: A total of 216 patients with acoustic neuroma (mean age 55 years, 58% women) were included. Ninety eight patients (45.4%) pursued surgical resection, 118 patients (54.6%) pursued active surveillance. Surgical treatment was significantly associated with patient age less than 65, higher grade tumors, growing tumors, larger volume tumors, lower word discrimination scores, Class D hearing, headache, and vertigo as presenting symptoms, higher number of total symptoms, and higher headache severity scores (p < 0.05). There was no significant association between surgical intervention and preoperative quality of life, depression, and self-esteem scores. On multiple logistic regression analysis, the likelihood of undergoing surgical resection significantly decreased for patients older than age 65 (odds ratio [OR] 0.19; 0.05-0.69) and increased in patients with medium (OR 4.34; 1.36-13.81), moderately large (OR 33.47; 5.72-195.83), large grade tumors (OR 56.63; 4.02-518.93), tumor growth present (OR 4.51; 1.66-12.28), Class D hearing (OR 3.96; 1.29-12.16), and higher headache severity scores (OR 1.03; 95% confidence interval [CI] 1.01-1.05). The likelihood of undergoing surgical resection was completely predictive for giant grade tumors and not significant for small grade tumors and Class B or C hearing. Conclusions: Non-elderly acoustic neuroma patients with larger tumors, growing tumors, significant hearing loss, and worse headaches are more likely to pursue surgical resection rather than active surveillance. Psychological factors such as quality of life, depression, and self-esteem do not seem to influence decision-making in this patient population.

Original languageEnglish (US)
Pages (from-to)392-399
Number of pages8
JournalOtology and Neurotology
Volume38
Issue number3
DOIs
StatePublished - Mar 1 2017

Fingerprint

Acoustic Neuroma
Decision Making
Odds Ratio
Neoplasms
Headache
Neurotology
Therapeutics
Hearing
Tertiary Healthcare
Psychometrics
Self Concept
Logistic Models
Regression Analysis
Quality of Life
Demography
Depression
Vertigo
Tumor Burden
Hearing Loss
Observational Studies

Keywords

  • Acoustic neuroma
  • Headache
  • Hearing loss
  • Patient-centered care
  • Psychometric
  • Shared decisionmaking
  • Surgery

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Sensory Systems
  • Clinical Neurology

Cite this

Multifactor Influences of Shared Decision-Making in Acoustic Neuroma Treatment. / Nellis, Jason C.; Sharon, Jeff D.; Pross, Seth E.; Ishii, Lisa Earnest; Ishii, Masaru; Dey, Jacob K.; Francis, Howard W.

In: Otology and Neurotology, Vol. 38, No. 3, 01.03.2017, p. 392-399.

Research output: Contribution to journalArticle

Nellis, Jason C. ; Sharon, Jeff D. ; Pross, Seth E. ; Ishii, Lisa Earnest ; Ishii, Masaru ; Dey, Jacob K. ; Francis, Howard W. / Multifactor Influences of Shared Decision-Making in Acoustic Neuroma Treatment. In: Otology and Neurotology. 2017 ; Vol. 38, No. 3. pp. 392-399.
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AU - Dey, Jacob K.

AU - Francis, Howard W.

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