Purpose. - Multidrug resistant tuberculosis (MDR-Tb) is a threat to tuberculosis control programmes. Data from MDR-Tb surveillance in France since 1992 are reported. Design. - Annual surveys were performed to collect all culture-positive cases of tuberculosis in France. Information on MDR-Tb cases included age, sex, country of birth, site of Th, HIV co-infection, date of first diagnosis of Tb and drug susceptibility. Results. - The annual prevalence of MDR-Tb cases was 0.6% on average and remained stable during the study period. A majority of MDR-Tb cases were male (70%), foreign-born (56%), and previously treated (66%). HIV co-infection, present in 21% of patients, was associated with primary MDR-Tb. Among MDR-Tb cases, 16% have been notified at least two different years suggesting they remained sources of MDR infection for long. Conclusion. - The low and stable prevalence rate of MDR-Tb reflects the adequate treatment of new cases of tuberculosis in France. However, because 16% of notified MDR-Tb cases remained culture-positive for years, there is room for improved treatment of these cases.
|Journal||Medecine et Maladies Infectieuses|
|Issue number||SUPPL. 3|
|Publication status||Published - Mar 1 2003|
- Multidrug resistance
- Mycobacterium tuberculosis
ASJC Scopus subject areas
- Infectious Diseases