La multirésistance (MDR) de Mycobacterium tuberculosis aux antibiotiques en France depuis 1992

Translated title of the contribution: Multidrug resistance (MDR) of Mycobacterium tuberculosis in France since 1992

J. Robert, D. Trystram, C. Truffot, J. Grosset

Research output: Contribution to journalArticle

Abstract

Purpose. - Multidrug resistant tuberculosis (MDR-Tb) is a threat to tuberculosis control programmes. Data from MDR-Tb surveillance in France since 1992 are reported. Design. - Annual surveys were performed to collect all culture-positive cases of tuberculosis in France. Information on MDR-Tb cases included age, sex, country of birth, site of Th, HIV co-infection, date of first diagnosis of Tb and drug susceptibility. Results. - The annual prevalence of MDR-Tb cases was 0.6% on average and remained stable during the study period. A majority of MDR-Tb cases were male (70%), foreign-born (56%), and previously treated (66%). HIV co-infection, present in 21% of patients, was associated with primary MDR-Tb. Among MDR-Tb cases, 16% have been notified at least two different years suggesting they remained sources of MDR infection for long. Conclusion. - The low and stable prevalence rate of MDR-Tb reflects the adequate treatment of new cases of tuberculosis in France. However, because 16% of notified MDR-Tb cases remained culture-positive for years, there is room for improved treatment of these cases.

Original languageFrench
JournalMedecine et Maladies Infectieuses
Volume33
Issue numberSUPPL. 3
Publication statusPublished - Mar 1 2003
Externally publishedYes

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Keywords

  • Multidrug resistance
  • Mycobacterium tuberculosis
  • Tuberculosis

ASJC Scopus subject areas

  • Infectious Diseases

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