Multidisciplinary prevention and management strategies for colorectal cancer and cardiovascular disease

Seamus Whelton, Philipp Berning, Roger S. Blumenthal, Catherine Handy Marshall, Seth S. Martin, Martin Bødtker Mortensen, Michael J. Blaha, Omar Dzaye

Research output: Contribution to journalReview articlepeer-review

Abstract

Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide. Their numerous shared and modifiable risk factors underscore the importance of effective prevention strategies for these largely preventable diseases. Conventionally regarded as separate disease entities, clear pathophysiological links and overlapping risk factors represent an opportunity for synergistic collaborative efforts of oncologists and cardiologists. In addition, current CRC treatment approaches can exert cardiotoxicity and thus increase CVD risk. Given the complex interplay of both diseases and increasing numbers of CRC survivors who are at increased risk for CVD, multidisciplinary cardio-oncological approaches are warranted for optimal patient care from primary prevention to acute disease treatment and long-term surveillance.

Original languageEnglish (US)
JournalEuropean Journal of Internal Medicine
DOIs
StateAccepted/In press - 2021

Keywords

  • Cardio-oncology
  • Cardiovascular disease
  • Colorectal cancer
  • Prevention

ASJC Scopus subject areas

  • Internal Medicine

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