Multidetector computed tomography in the evaluation of hereditary multiple exostoses

Robert M. Kwee, Laura M. Fayad, Elliot K. Fishman, Jan Fritz

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Hereditary multiple exostoses (HME) is an autosomal dominant disorder characterized by the formation of multiple osteochondromas. Because of its superior soft tissue contrast and absence of ionizing radiation, magnetic resonance imaging is the first choice imaging technique for the evaluation of complex lesions and complications related to HME. However, multidetector computed tomography (MDCT) also can be of value in the evaluation of patients with HME, which is reviewed in this article. Topics outlined are low-dose MDCT technique, 3-dimensional visualization techniques, typical MDCT appearances, differential diagnostic considerations, and the usefulness of MDCT in the assessment of emergent and non-emergent complications related to HME, among which spinal cord compression, pneumothorax and hematothorax, pseudoaneurysms, fractures, growth disturbances, chondrosarcoma transformation, and muscular and peripheral nerve involvement.

Original languageEnglish (US)
Pages (from-to)383-391
Number of pages9
JournalEuropean Journal of Radiology
Issue number2
StatePublished - Feb 1 2016


  • CT
  • Computed tomography
  • HME
  • Hereditary multiple exostoses
  • MDCT
  • Multidetector
  • Osteochondroma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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