Multichannel Electrogastrography (EGG) in normal subjects: A multicenter study

Hrair P. Simonian, Kashyap Panganamamula, Henry P. Parkman, Xiaohong Xu, Jiande Z. Chen, Greger Lindberg, Hui Xu, Chi Shao, Mei Yun Ke, Michael Lykke, Per Hansen, Bjorn Barner, Henrik Buhl

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


The aim of this study was to record gastric myoelectric activity using multichannel electrogastrography (EGG) and to determine if there are differences due to age, gender, body mass, and study location. In 61 normal subjects from four centers, fasting multichannel EGG was recorded for 1 h, followed by two 1-h postprandial recordings after a test meal. Variables assessed included dominant frequency (DF) and its power, percentage time in 2- to 4-cpm frequency, and percentage slow-wave coupling (%SWC). There were no significant differences in EGG parameters with respect to gender or age. Subjects with a BMI >25 had a decrease in the absolute DF power but a similar increase in the postprandial DF power. Subjects with a BMI >25 had a postprandial decrease in the %SWC compared to those with a BMI <25. There was a decrease in postprandial %SWC in European/Asian centers compared to American centers. In conclusion, multichannel EGG provides assessment of electrical slow-wave coupling in addition to determining dominant frequency, power, and percentage normal rhythm. This multicenter study of normal subjects shows similar multichannel EGG values among different genders and ages. Body mass and ethnicity may impact on some of the EGG values.

Original languageEnglish (US)
Pages (from-to)594-601
Number of pages8
JournalDigestive diseases and sciences
Issue number4
StatePublished - Apr 2004
Externally publishedYes


  • Electrogastrography
  • Gastric motility

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology


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