Multi-slice proton MR spectroscopy and diffusion-weighted imaging in methylmalonic acidemia: Report of two cases and review of the literature

Ba Chinh Trinh, Elias R. Melhem, Peter B. Barker

Research output: Contribution to journalArticle


Methylmalonic acidemia is an inborn disorder of amino acid metabolism that commonly presents with neurologic deficits. We present the results of multi-slice proton MR spectroscopy and diffusion-weighted imaging of the brain in two patients with methylmalonic acidemia. The findings consisted of restricted diffusion and elevated lactate in the globi pallidi, compatible with acute infarction (patient 1) and elevated lactate in CSF (patient 2).

Original languageEnglish (US)
Pages (from-to)831-833
Number of pages3
JournalAmerican Journal of Neuroradiology
Issue number5
StatePublished - May 1 2001


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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