Multi-gram scale synthesis of FR180204

Samarjit Patnaik, Harry C Dietz, Wei Zheng, Christopher Austin, Juan J. Marugan

Research output: Contribution to journalArticle

Abstract

(Chemical Equation Presented) A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.

Original languageEnglish (US)
Pages (from-to)8870-8873
Number of pages4
JournalJournal of Organic Chemistry
Volume74
Issue number22
DOIs
StatePublished - Nov 20 2009

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FR 180204

ASJC Scopus subject areas

  • Organic Chemistry

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Patnaik, S., Dietz, H. C., Zheng, W., Austin, C., & Marugan, J. J. (2009). Multi-gram scale synthesis of FR180204. Journal of Organic Chemistry, 74(22), 8870-8873. https://doi.org/10.1021/jo901835m

Multi-gram scale synthesis of FR180204. / Patnaik, Samarjit; Dietz, Harry C; Zheng, Wei; Austin, Christopher; Marugan, Juan J.

In: Journal of Organic Chemistry, Vol. 74, No. 22, 20.11.2009, p. 8870-8873.

Research output: Contribution to journalArticle

Patnaik, S, Dietz, HC, Zheng, W, Austin, C & Marugan, JJ 2009, 'Multi-gram scale synthesis of FR180204', Journal of Organic Chemistry, vol. 74, no. 22, pp. 8870-8873. https://doi.org/10.1021/jo901835m
Patnaik S, Dietz HC, Zheng W, Austin C, Marugan JJ. Multi-gram scale synthesis of FR180204. Journal of Organic Chemistry. 2009 Nov 20;74(22):8870-8873. https://doi.org/10.1021/jo901835m
Patnaik, Samarjit ; Dietz, Harry C ; Zheng, Wei ; Austin, Christopher ; Marugan, Juan J. / Multi-gram scale synthesis of FR180204. In: Journal of Organic Chemistry. 2009 ; Vol. 74, No. 22. pp. 8870-8873.
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