Multi-component nanorods for vaccination applications

A. K. Salem, C. F. Hung, T. W. Kim, T. C. Wu, P. C. Searson, K. W. Leong

Research output: Contribution to journalArticle

Abstract

Immune responses from Au/Ni nanorods prepared by electrochemical deposition in alumina templates are evaluated in C57BL/6 mice. When the nanorods are bombarded into skin, they generate a strong CDS T-cell and antibody response. When pcDNA3 is bound to the Ni segment of the nanorod, it provides a strong immunostimulatory adjuvant effect to the antigen bound on the Au segment.

Original languageEnglish (US)
Pages (from-to)484-487
Number of pages4
JournalNanotechnology
Volume16
Issue number4
DOIs
StatePublished - Apr 1 2005

    Fingerprint

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this