Mucosa-associated lymphoid tissue disease in the lung: When should it be treated as lymphoma?

Sean M. Studer, Leisha A. Emens, David Zaas, Charles M. Wiener, Edward F. Haponik

Research output: Contribution to journalArticle

Abstract

We report a patient with mucosa-associated lymphoid tissue (MALT) disease with gastric, bone marrow, and pulmonary involvement and discuss features of this condition that justify its classification and treatment as a lymphoma. The chest radiographic appearance of MALT disease is nondiagnostic and often suggests a range of pulmonary diagnoses. Additionally, while tissue histology may identify features of MALT hypertrophy, there is often difficulty establishing the disease as either benign hyperplasia or low-grade lymphoma on the basis of pathologic criteria. Even when indicators of malignancy are present, the optimal treatment approach may remain unclear. For this reason, decisions regarding treatment are often based on the biologic behavior of a particular patient's MALT disease rather than the strict histologic classification as benign or malignant.

Original languageEnglish (US)
Pages (from-to)34-37
Number of pages4
JournalJournal of Bronchology
Volume10
Issue number1
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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