Much Ado about Zero

Jef D. Boeke, David Fenyo

Research output: Contribution to journalShort survey

Abstract

LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.

Original languageEnglish (US)
Pages (from-to)534-535
Number of pages2
JournalCell
Volume163
Issue number3
DOIs
StatePublished - Oct 22 2015

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Boeke, J. D., & Fenyo, D. (2015). Much Ado about Zero. Cell, 163(3), 534-535. https://doi.org/10.1016/j.cell.2015.10.033