MRI shows dorsal lesions and spinal cord atrophy in chronic sensory neuronopathies

Marcondes C. França, Anelyssa D'Abreu, Verônica A. Zanardi, Andreia Vasconcellos Faria, Iscia Lopes-Cendes, Anamarli Nucci, Fernando Cendes

Research output: Contribution to journalArticle

Abstract

BACKGROUND AND PURPOSE: Sensory neuronopathies (SN) represent a specific subgroup of peripheral nervous system diseases, characterized by degeneration of dorsal root ganglia (DRG) and its projections. We tried to estimate the frequency and extent of spinal cord MRI abnormalities in a group of patients with SN and correlate these with clinical and neurophysiological features. METHODS: We performed spinal cord MRI scans in 16 chronic SN patients. Images were analyzed for the presence of posterior hyperintense lesions on T2WI and cord areas at C3 level were obtained using a previously validated method. A group of 14 healthy controls with similar age and gender distribution was used for comparison. ANOVA was employed for statistical analysis. RESULTS: Posterior T2WI lesions were found in 13 out of 16 patients. Cord areas were significantly smaller in SN patients than controls (84.3 × 97.2 mm2, P

Original languageEnglish (US)
Pages (from-to)168-172
Number of pages5
JournalJournal of Neuroimaging
Volume18
Issue number2
DOIs
StatePublished - Apr 2008
Externally publishedYes

Fingerprint

Atrophy
Spinal Cord
Age Distribution
Spinal Ganglia
Peripheral Nervous System Diseases
Analysis of Variance
Magnetic Resonance Imaging

Keywords

  • Magnetic resonance imaging
  • Sensory neuronopathy
  • Spinal cord

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Neuroscience(all)
  • Radiological and Ultrasound Technology

Cite this

França, M. C., D'Abreu, A., Zanardi, V. A., Faria, A. V., Lopes-Cendes, I., Nucci, A., & Cendes, F. (2008). MRI shows dorsal lesions and spinal cord atrophy in chronic sensory neuronopathies. Journal of Neuroimaging, 18(2), 168-172. https://doi.org/10.1111/j.1552-6569.2007.00193.x

MRI shows dorsal lesions and spinal cord atrophy in chronic sensory neuronopathies. / França, Marcondes C.; D'Abreu, Anelyssa; Zanardi, Verônica A.; Faria, Andreia Vasconcellos; Lopes-Cendes, Iscia; Nucci, Anamarli; Cendes, Fernando.

In: Journal of Neuroimaging, Vol. 18, No. 2, 04.2008, p. 168-172.

Research output: Contribution to journalArticle

França, MC, D'Abreu, A, Zanardi, VA, Faria, AV, Lopes-Cendes, I, Nucci, A & Cendes, F 2008, 'MRI shows dorsal lesions and spinal cord atrophy in chronic sensory neuronopathies', Journal of Neuroimaging, vol. 18, no. 2, pp. 168-172. https://doi.org/10.1111/j.1552-6569.2007.00193.x
França, Marcondes C. ; D'Abreu, Anelyssa ; Zanardi, Verônica A. ; Faria, Andreia Vasconcellos ; Lopes-Cendes, Iscia ; Nucci, Anamarli ; Cendes, Fernando. / MRI shows dorsal lesions and spinal cord atrophy in chronic sensory neuronopathies. In: Journal of Neuroimaging. 2008 ; Vol. 18, No. 2. pp. 168-172.
@article{25226a528dff4ef8a39346e49b6baca4,
title = "MRI shows dorsal lesions and spinal cord atrophy in chronic sensory neuronopathies",
abstract = "BACKGROUND AND PURPOSE: Sensory neuronopathies (SN) represent a specific subgroup of peripheral nervous system diseases, characterized by degeneration of dorsal root ganglia (DRG) and its projections. We tried to estimate the frequency and extent of spinal cord MRI abnormalities in a group of patients with SN and correlate these with clinical and neurophysiological features. METHODS: We performed spinal cord MRI scans in 16 chronic SN patients. Images were analyzed for the presence of posterior hyperintense lesions on T2WI and cord areas at C3 level were obtained using a previously validated method. A group of 14 healthy controls with similar age and gender distribution was used for comparison. ANOVA was employed for statistical analysis. RESULTS: Posterior T2WI lesions were found in 13 out of 16 patients. Cord areas were significantly smaller in SN patients than controls (84.3 × 97.2 mm2, P",
keywords = "Magnetic resonance imaging, Sensory neuronopathy, Spinal cord",
author = "Fran{\cc}a, {Marcondes C.} and Anelyssa D'Abreu and Zanardi, {Ver{\^o}nica A.} and Faria, {Andreia Vasconcellos} and Iscia Lopes-Cendes and Anamarli Nucci and Fernando Cendes",
year = "2008",
month = "4",
doi = "10.1111/j.1552-6569.2007.00193.x",
language = "English (US)",
volume = "18",
pages = "168--172",
journal = "Journal of Neuroimaging",
issn = "1051-2284",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - MRI shows dorsal lesions and spinal cord atrophy in chronic sensory neuronopathies

AU - França, Marcondes C.

AU - D'Abreu, Anelyssa

AU - Zanardi, Verônica A.

AU - Faria, Andreia Vasconcellos

AU - Lopes-Cendes, Iscia

AU - Nucci, Anamarli

AU - Cendes, Fernando

PY - 2008/4

Y1 - 2008/4

N2 - BACKGROUND AND PURPOSE: Sensory neuronopathies (SN) represent a specific subgroup of peripheral nervous system diseases, characterized by degeneration of dorsal root ganglia (DRG) and its projections. We tried to estimate the frequency and extent of spinal cord MRI abnormalities in a group of patients with SN and correlate these with clinical and neurophysiological features. METHODS: We performed spinal cord MRI scans in 16 chronic SN patients. Images were analyzed for the presence of posterior hyperintense lesions on T2WI and cord areas at C3 level were obtained using a previously validated method. A group of 14 healthy controls with similar age and gender distribution was used for comparison. ANOVA was employed for statistical analysis. RESULTS: Posterior T2WI lesions were found in 13 out of 16 patients. Cord areas were significantly smaller in SN patients than controls (84.3 × 97.2 mm2, P

AB - BACKGROUND AND PURPOSE: Sensory neuronopathies (SN) represent a specific subgroup of peripheral nervous system diseases, characterized by degeneration of dorsal root ganglia (DRG) and its projections. We tried to estimate the frequency and extent of spinal cord MRI abnormalities in a group of patients with SN and correlate these with clinical and neurophysiological features. METHODS: We performed spinal cord MRI scans in 16 chronic SN patients. Images were analyzed for the presence of posterior hyperintense lesions on T2WI and cord areas at C3 level were obtained using a previously validated method. A group of 14 healthy controls with similar age and gender distribution was used for comparison. ANOVA was employed for statistical analysis. RESULTS: Posterior T2WI lesions were found in 13 out of 16 patients. Cord areas were significantly smaller in SN patients than controls (84.3 × 97.2 mm2, P

KW - Magnetic resonance imaging

KW - Sensory neuronopathy

KW - Spinal cord

UR - http://www.scopus.com/inward/record.url?scp=41549112480&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41549112480&partnerID=8YFLogxK

U2 - 10.1111/j.1552-6569.2007.00193.x

DO - 10.1111/j.1552-6569.2007.00193.x

M3 - Article

C2 - 18380696

AN - SCOPUS:41549112480

VL - 18

SP - 168

EP - 172

JO - Journal of Neuroimaging

JF - Journal of Neuroimaging

SN - 1051-2284

IS - 2

ER -