MRI of hyperpolarized 3He gas in human paranasal sinuses

Rahim R. Rizi, Ivan E. Dimitrov, Alan Thompson, Gordon Jones, Tom R. Gentile, Masaru Ishii, Ravinder Reddy, Mitchell D. Schnall, John S. Leigh

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


In this study, MRI of hyperpolarized 3He gas in human paranasal sinuses is presented. Helium images were obtained at 1.5 T, using a surface coil and a 2D, fast gradient-echo sequence with a nominal constant flip angle of 12°. Coronal images of 20-mm thick slices were generated and compared with proton images of the corresponding sections. The images enable visualization of the paranasal sinuses and the nasal cavity, suggesting a potential use of this method not only in identifying the anatomical configuration of these pneumatic spaces, but also in assessing sinus ventilation.

Original languageEnglish (US)
Pages (from-to)865-868
Number of pages4
JournalMagnetic resonance in medicine
Issue number6
StatePublished - Jun 1998
Externally publishedYes


  • He
  • Hyperpolarized gas
  • MRI
  • Paranasal sinuses

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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