MRI of CEST-based reporter gene

Guanshu Liu, Assaf A. Gilad

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In recent years, several reporter genes have been designed for non-invasive magnetic resonance imaging (MRI). Here, we offer a brief summary of recent advances in MRI reporter gene technology, as well as elaborated protocols for cloning, expression, and imaging of reporter genes based on a chemical exchange saturation transfer (CEST) method. These protocols emphasize new developments in CEST-MRI data acquisition and processing.

Original languageEnglish (US)
Title of host publicationIn vivo NMR Imaging
Subtitle of host publicationMethods and Protocols
EditorsLeif Schroder, Cornelius Faber
Pages733-746
Number of pages14
DOIs
StatePublished - Oct 24 2011

Publication series

NameMethods in Molecular Biology
Volume771
ISSN (Print)1064-3745

Keywords

  • CEST
  • MRI
  • MRI reporter gene
  • in vivo MR imaging
  • molecular imaging

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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