MRI in mouse developmental biology

Daniel H. Turnbull, Susumu Mori

Research output: Contribution to journalReview articlepeer-review

Abstract

Mice are used in many studies to determine the role of genetic and molecular factors in mammalian development and human congenital diseases. MRI has emerged as a major method for analyzing mutant and transgenic phenotypes in developing mice, at both embryonic and neonatal stages. Progress in this area is reviewed, with emphasis on the use of MRI to analyze cardiovascular and neural development in mice. Comparisons are made with other imaging technologies, including optical and ultrasound imaging, discussing the potential strengths and weaknesses of MRI and identifying the future challenges for MRI in mouse developmental biology.

Original languageEnglish (US)
Pages (from-to)265-274
Number of pages10
JournalNMR in biomedicine
Volume20
Issue number3
DOIs
StatePublished - May 2007

Keywords

  • Brain
  • Cardiovascular
  • Diffusion tensor imaging
  • MRI

ASJC Scopus subject areas

  • Molecular Medicine
  • Radiology Nuclear Medicine and imaging
  • Spectroscopy

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