MRI-guided region of interest placement on emission computed tomograms

Gordon J. Harris; Godfrey D. Pearlson

doi:10.1016/0925-4927(93)90024-C

MRI-guided region of interest placement on emission computed tomograms

Gordon J. Harris, Godfrey D. Pearlson

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The reliability of the placement of regions of interest (ROIs) on emission computed tomograms (ECT) with a semi-automated magnetic resonance image (MRI)-guided method was compared with the reliability of manual ROI placement. MRI-defined regions were transferred to the registered, co-planar ECT image after accounting for inter-image differences in rotation, translation, and scaling. Six single photon emission computed tomographic (SPECT) scans of normal control subjects were rated for caudate perfusion using the radiotracer N-isopropyl[I-¹²³]-iodoamphetamine (IMP). The MRI-guided method had higher interrater reliability, lower variance of region location and lower variance of region activity than the manual method. The manual method recorded higher mean regional activity than the MRI-guided method, possibly due to sample bias inherent in the manual method.

Original language	English (US)
Pages (from-to)	57-63
Number of pages	7
Journal	Psychiatry Research: Neuroimaging
Volume	50
Issue number	1
DOIs	https://doi.org/10.1016/0925-4927(93)90024-C
State	Published - Apr 1993

Keywords

Magnetic resonance imaging
image registration
single photon emission computed tomography

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

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10.1016/0925-4927(93)90024-C

Cite this

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abstract = "The reliability of the placement of regions of interest (ROIs) on emission computed tomograms (ECT) with a semi-automated magnetic resonance image (MRI)-guided method was compared with the reliability of manual ROI placement. MRI-defined regions were transferred to the registered, co-planar ECT image after accounting for inter-image differences in rotation, translation, and scaling. Six single photon emission computed tomographic (SPECT) scans of normal control subjects were rated for caudate perfusion using the radiotracer N-isopropyl[I-123]-iodoamphetamine (IMP). The MRI-guided method had higher interrater reliability, lower variance of region location and lower variance of region activity than the manual method. The manual method recorded higher mean regional activity than the MRI-guided method, possibly due to sample bias inherent in the manual method.",

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AU - Pearlson, Godfrey D.

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KW - image registration

KW - single photon emission computed tomography

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MRI-guided region of interest placement on emission computed tomograms

Abstract

Keywords

ASJC Scopus subject areas

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