MRI-guided coronary catheterization and PTCA: A feasibility study on a dog model

Jean Michel Serfaty, Xiaoming Yang, Thomas K. Foo, Ananda Kumar, Andrew Derbyshire, Ergin Atalar

Research output: Contribution to journalArticle

Abstract

The aim of this work was to demonstrate the feasibility of MRI-guided coronary artery catheterization and intervention in a dog model. Experiments were performed on 10 healthy dogs. A 9F introducer sheath was placed through a right carotid artery cutdown. A prototype 0.014-inch coronary MRI guidewire, a prototype 7 French MRI-guiding catheter, and two flexible surface coils were connected to a GE 1.5 T CV/i scanner for simultaneous visualization of the guidewire, guiding catheter, and chest anatomy. Images were displayed in real time on an in-room monitor. A nongated, single-slice fast gradient-echo sequence was used to obtain real-time images of the catheters and background anatomy during the intervention. Fifteen selective catheterizations were attempted in the coronary arteries, and all were successful. Selective injection of diluted gadolinium into the MRI-guiding catheter provided dynamic 2D projection coronary angiography in all cases, confirming successful catheterization. Percutaneous transluminal coronary angioplasty (PTCA) was attempted after two catheterizations, and all attempts were successful. Inflation of the balloon angioplasty catheter was performed successfully in the left anterior and circumflex arteries. Our results indicate that coronary artery catheterization and intracoronary balloon angioplasty are feasible with MRI guidance only. MRI guidance may be used as an alternative to X-ray guidance in coronary artery interventions in the future.

Original languageEnglish (US)
Pages (from-to)258-263
Number of pages6
JournalMagnetic Resonance in Medicine
Volume49
Issue number2
DOIs
StatePublished - Feb 1 2003

Fingerprint

Coronary Balloon Angioplasty
Feasibility Studies
Catheterization
Catheters
Dogs
Coronary Vessels
Balloon Angioplasty
Anatomy
Economic Inflation
Gadolinium
Coronary Angiography
Carotid Arteries
Thorax
Arteries
X-Rays
Injections

Keywords

  • Arteries
  • Arteriosclerosis
  • Catheter and catheterization
  • Coronary vessels
  • Magnetic resonance imaging
  • Transluminal angioplasty

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Serfaty, J. M., Yang, X., Foo, T. K., Kumar, A., Derbyshire, A., & Atalar, E. (2003). MRI-guided coronary catheterization and PTCA: A feasibility study on a dog model. Magnetic Resonance in Medicine, 49(2), 258-263. https://doi.org/10.1002/mrm.10393

MRI-guided coronary catheterization and PTCA : A feasibility study on a dog model. / Serfaty, Jean Michel; Yang, Xiaoming; Foo, Thomas K.; Kumar, Ananda; Derbyshire, Andrew; Atalar, Ergin.

In: Magnetic Resonance in Medicine, Vol. 49, No. 2, 01.02.2003, p. 258-263.

Research output: Contribution to journalArticle

Serfaty, JM, Yang, X, Foo, TK, Kumar, A, Derbyshire, A & Atalar, E 2003, 'MRI-guided coronary catheterization and PTCA: A feasibility study on a dog model', Magnetic Resonance in Medicine, vol. 49, no. 2, pp. 258-263. https://doi.org/10.1002/mrm.10393
Serfaty, Jean Michel ; Yang, Xiaoming ; Foo, Thomas K. ; Kumar, Ananda ; Derbyshire, Andrew ; Atalar, Ergin. / MRI-guided coronary catheterization and PTCA : A feasibility study on a dog model. In: Magnetic Resonance in Medicine. 2003 ; Vol. 49, No. 2. pp. 258-263.
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