TY - JOUR
T1 - MRI for the Assessment of Myocardial Viability
AU - Weinsaft, Jonathan W.
AU - Klem, Igor
AU - Judd, Robert M.
PY - 2007/11/1
Y1 - 2007/11/1
N2 - Accurate distinction between viable and infarcted myocardium is important for assessment of patients who have cardiac dysfunction. Through the technique of delayed-enhancement MRI (DE-MRI), viable and infarcted myocardium can be simultaneously identified in a manner that closely correlates with histopathology findings. This article provides an overview of experimental data establishing the physiologic basis of DE-MRI-evidenced hyperenhancement as a tissue-specific marker of myocardial infarction. Clinical data concerning the utility of transmural extent of hyperenhancement for predicting response to medical and revascularization therapy are reviewed. Studies directly comparing DE-MRI to other viability imaging techniques are presented, and emerging applications for DE-MRI are discussed.
AB - Accurate distinction between viable and infarcted myocardium is important for assessment of patients who have cardiac dysfunction. Through the technique of delayed-enhancement MRI (DE-MRI), viable and infarcted myocardium can be simultaneously identified in a manner that closely correlates with histopathology findings. This article provides an overview of experimental data establishing the physiologic basis of DE-MRI-evidenced hyperenhancement as a tissue-specific marker of myocardial infarction. Clinical data concerning the utility of transmural extent of hyperenhancement for predicting response to medical and revascularization therapy are reviewed. Studies directly comparing DE-MRI to other viability imaging techniques are presented, and emerging applications for DE-MRI are discussed.
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U2 - 10.1016/j.mric.2007.08.007
DO - 10.1016/j.mric.2007.08.007
M3 - Review article
C2 - 17976589
AN - SCOPUS:35548939081
SN - 1064-9689
VL - 15
SP - 505
EP - 525
JO - Magnetic Resonance Imaging Clinics of North America
JF - Magnetic Resonance Imaging Clinics of North America
IS - 4
ER -