Abstract
Background.: Changes in right ventricular mass and ejection fraction after single-lung transplantation for pulmonary hypertension are poorly understood. Methods.: To complement functional data provided by echocardiography, radionuclide ventriculography, and right heart catheterization, magnetic resonance imaging was used to assess right ventricular function in 5 single-lung transplant recipients with preoperative pulmonary hypertension and right ventricular dysfunction (right ventricular ejection fraction, 0.21 ± 0.09). The right and left ventricular mass, ejection fraction, and mass ratio (left ventricular mass/right ventricular mass) were calculated from the magnetic resonance images. Results.: The mean pulmonary artery pressure fell from 72 ± 18 to 21 ± 8 mm Hg after transplantation. At 3 months after transplantation both the left ventricular and right ventricular ejection fractions approached normal values, as shown by both radionuclide ventriculography and magnetic resonance imaging, but the right ventricular mass remained abnormally high with slightly low mass ratios. By 1 year both the left ventricular and right ventricular masses had regressed to normal with near-normal mass ratios. Conclusions.: Right ventricular performance returns to nearly normal early after transplantation, but the right ventricular mass regresses over a more prolonged time. Cine magnetic resonance imaging provides a noninvasive means of assessing changes in right ventricular function and mass after lung transplantation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 268-271 |
| Number of pages | 4 |
| Journal | Annals of Thoracic Surgery |
| Volume | 60 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1995 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Surgery
Cite this
MRI complements standard assessment of right ventricular function after lung transplantation. / Frist, William H.; Lorenz, Christine H.; Walker, Eloisa S.; Loyd, James E.; Stewart, James R.; Graham, Thomas P.; Pearlstein, Daryl P.; Key, Steven P.; Merrill, Walter H.
In: Annals of Thoracic Surgery, Vol. 60, No. 2, 1995, p. 268-271.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - MRI complements standard assessment of right ventricular function after lung transplantation
AU - Frist, William H.
AU - Lorenz, Christine H.
AU - Walker, Eloisa S.
AU - Loyd, James E.
AU - Stewart, James R.
AU - Graham, Thomas P.
AU - Pearlstein, Daryl P.
AU - Key, Steven P.
AU - Merrill, Walter H.
PY - 1995
Y1 - 1995
N2 - Background.: Changes in right ventricular mass and ejection fraction after single-lung transplantation for pulmonary hypertension are poorly understood. Methods.: To complement functional data provided by echocardiography, radionuclide ventriculography, and right heart catheterization, magnetic resonance imaging was used to assess right ventricular function in 5 single-lung transplant recipients with preoperative pulmonary hypertension and right ventricular dysfunction (right ventricular ejection fraction, 0.21 ± 0.09). The right and left ventricular mass, ejection fraction, and mass ratio (left ventricular mass/right ventricular mass) were calculated from the magnetic resonance images. Results.: The mean pulmonary artery pressure fell from 72 ± 18 to 21 ± 8 mm Hg after transplantation. At 3 months after transplantation both the left ventricular and right ventricular ejection fractions approached normal values, as shown by both radionuclide ventriculography and magnetic resonance imaging, but the right ventricular mass remained abnormally high with slightly low mass ratios. By 1 year both the left ventricular and right ventricular masses had regressed to normal with near-normal mass ratios. Conclusions.: Right ventricular performance returns to nearly normal early after transplantation, but the right ventricular mass regresses over a more prolonged time. Cine magnetic resonance imaging provides a noninvasive means of assessing changes in right ventricular function and mass after lung transplantation.
AB - Background.: Changes in right ventricular mass and ejection fraction after single-lung transplantation for pulmonary hypertension are poorly understood. Methods.: To complement functional data provided by echocardiography, radionuclide ventriculography, and right heart catheterization, magnetic resonance imaging was used to assess right ventricular function in 5 single-lung transplant recipients with preoperative pulmonary hypertension and right ventricular dysfunction (right ventricular ejection fraction, 0.21 ± 0.09). The right and left ventricular mass, ejection fraction, and mass ratio (left ventricular mass/right ventricular mass) were calculated from the magnetic resonance images. Results.: The mean pulmonary artery pressure fell from 72 ± 18 to 21 ± 8 mm Hg after transplantation. At 3 months after transplantation both the left ventricular and right ventricular ejection fractions approached normal values, as shown by both radionuclide ventriculography and magnetic resonance imaging, but the right ventricular mass remained abnormally high with slightly low mass ratios. By 1 year both the left ventricular and right ventricular masses had regressed to normal with near-normal mass ratios. Conclusions.: Right ventricular performance returns to nearly normal early after transplantation, but the right ventricular mass regresses over a more prolonged time. Cine magnetic resonance imaging provides a noninvasive means of assessing changes in right ventricular function and mass after lung transplantation.
UR - http://www.scopus.com/inward/record.url?scp=0029129387&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029129387&partnerID=8YFLogxK
U2 - 10.1016/0003-4975(95)00365-R
DO - 10.1016/0003-4975(95)00365-R
M3 - Article
C2 - 7646085
AN - SCOPUS:0029129387
VL - 60
SP - 268
EP - 271
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 2
ER -