MR spectroscopy and spectroscopic imaging of the brain

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Magnetic resonance spectroscopy (MRS) and the related technique of magnetic resonance spectroscopic imaging (MRSI) are widely used in both clinical and preclinical research for the non-invasive evaluation of brain metabolism. They are also used in medical practice, although their ultimate clinical value continues to be a source of discussion. This chapter reviews the general information content of brain spectra and commonly used protocols for both MRS and MRSI and also touches on data analysis methods and quantitation. The main focus is on proton MRS for application in humans, but many of the methods are also applicable to other nuclei and studies of animal models as well.

Original languageEnglish (US)
Title of host publicationMagnetic Resonance Neuroimaging
Subtitle of host publicationMethods and Protocols
EditorsMichel Modo, Jelte Bulte
Pages203-226
Number of pages24
DOIs
StatePublished - Dec 1 2010
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume711
ISSN (Print)1064-3745

    Fingerprint

Keywords

  • Brain
  • magnetic resonance spectroscopy
  • metabolites
  • spatial localization
  • spectroscopic imaging

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Zhu, H., & Barker, P. B. (2010). MR spectroscopy and spectroscopic imaging of the brain. In M. Modo, & J. Bulte (Eds.), Magnetic Resonance Neuroimaging: Methods and Protocols (pp. 203-226). (Methods in Molecular Biology; Vol. 711). https://doi.org/10.1007/978-1-61737-992-5_9