MR spectroscopy and spectroscopic imaging of the brain

Research output: Chapter in Book/Report/Conference proceedingChapter


Magnetic resonance spectroscopy (MRS) and the related technique of magnetic resonance spectroscopic imaging (MRSI) are widely used in both clinical and preclinical research for the non-invasive evaluation of brain metabolism. They are also used in medical practice, although their ultimate clinical value continues to be a source of discussion. This chapter reviews the general information content of brain spectra and commonly used protocols for both MRS and MRSI and also touches on data analysis methods and quantitation. The main focus is on proton MRS for application in humans, but many of the methods are also applicable to other nuclei and studies of animal models as well.

Original languageEnglish (US)
Title of host publicationMagnetic Resonance Neuroimaging
Subtitle of host publicationMethods and Protocols
EditorsMichel Modo, Jelte Bulte
Number of pages24
StatePublished - 2010
Externally publishedYes

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Brain
  • magnetic resonance spectroscopy
  • metabolites
  • spatial localization
  • spectroscopic imaging

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


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