MR spectroscopy and spectroscopic imaging of the brain

Research output: Contribution to journalArticle

Abstract

Magnetic resonance spectroscopy (MRS) and the related technique of magnetic resonance spectroscopic imaging (MRSI) are widely used in both clinical and preclinical research for the non-invasive evaluation of brain metabolism. They are also used in medical practice, although their ultimate clinical value continues to be a source of discussion. This chapter reviews the general information content of brain spectra and commonly used protocols for both MRS and MRSI and also touches on data analysis methods and quantitation. The main focus is on proton MRS for application in humans, but many of the methods are also applicable to other nuclei and studies of animal models as well.

Original languageEnglish (US)
Pages (from-to)203-226
Number of pages24
JournalMethods in molecular biology (Clifton, N.J.)
Volume711
DOIs
StatePublished - 2010
Externally publishedYes

Fingerprint

Neuroimaging
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Brain
Animal Models
Research
Proton Magnetic Resonance Spectroscopy

Keywords

  • Brain
  • magnetic resonance spectroscopy
  • metabolites
  • spatial localization
  • spectroscopic imaging

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Medicine(all)

Cite this

MR spectroscopy and spectroscopic imaging of the brain. / Zhu, He; Barker, Peter B.

In: Methods in molecular biology (Clifton, N.J.), Vol. 711, 2010, p. 203-226.

Research output: Contribution to journalArticle

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