TY - GEN
T1 - MR-Guided Tissue Puncture with On-Line Imaging for High-Resolution Theranostics
AU - Gunderman, Anthony L.
AU - Schmidt, Ehud J.
AU - Viswanathan, Akila N.
AU - Halperin, Henry R.
AU - Tokuda, Junichi
AU - Seethamraju, Ravi T.
AU - Chen, Yue
N1 - Funding Information:
This work was supported by UARK Chancellor's Fund for Innovation & Collaboration, R01-HL094610, R01-HL126092, R21-CA167800 and R01CA237005. The authors would like to thank Ben Fleming and Jason Bailey in the Mechanical Engineering Department at the University of Arkansas for their advice on machining fixtures and soldering.
Funding Information:
Research supported by UARK Chancellor's Fund for Innovation & Collaboration, R01-HL094610, R01-HL126092, and R21-CA167800.
Publisher Copyright:
© 2020 IEEE.
PY - 2020/11/18
Y1 - 2020/11/18
N2 - Methods of treating cancer, such as radiation or ablation, require tissue characterization prior to therapy, which today requires tissue biopsy. Typically, the tissue is excised from the body and examined by the pathologist with a microscope. In this paper, we present an alternative device that attempts to perform in-situ tissue characterization. We aim to accomplish this by utilizing a deflectable stylet (a metallic object employed for puncturing muscular tissue) in conjunction with MR Imaging along the stylet trajectory. We discuss the design and fabrication of an actively tracked deflectable stylet, the mechanism to deflect the stylet, and the system assembly, as well as the incorporation of the coils for MR Tracking and Imaging. Additionally, a preliminary evaluation of the system is presented to validate the feasibility of its use for high-resolution theranostics.
AB - Methods of treating cancer, such as radiation or ablation, require tissue characterization prior to therapy, which today requires tissue biopsy. Typically, the tissue is excised from the body and examined by the pathologist with a microscope. In this paper, we present an alternative device that attempts to perform in-situ tissue characterization. We aim to accomplish this by utilizing a deflectable stylet (a metallic object employed for puncturing muscular tissue) in conjunction with MR Imaging along the stylet trajectory. We discuss the design and fabrication of an actively tracked deflectable stylet, the mechanism to deflect the stylet, and the system assembly, as well as the incorporation of the coils for MR Tracking and Imaging. Additionally, a preliminary evaluation of the system is presented to validate the feasibility of its use for high-resolution theranostics.
KW - MR Imaging
KW - MR tracking
KW - Puncture Device
UR - http://www.scopus.com/inward/record.url?scp=85100265858&partnerID=8YFLogxK
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U2 - 10.1109/ISMR48331.2020.9312942
DO - 10.1109/ISMR48331.2020.9312942
M3 - Conference contribution
AN - SCOPUS:85100265858
T3 - 2020 International Symposium on Medical Robotics, ISMR 2020
SP - 57
EP - 61
BT - 2020 International Symposium on Medical Robotics, ISMR 2020
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2020 International Symposium on Medical Robotics, ISMR 2020
Y2 - 18 November 2020 through 20 November 2020
ER -