MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization

Daniel Herzka, M. S. Kotys, S. Krueger, B. J. Traughber, J. Heroux, A. M. Gharib, J. Ohayon, S. Weiss, R. I. Pettigrew, B. J. Wood

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Excitation emission spectroscopy (EES) has been used in the past to characterize many different types of tissue. This technique uses multiple excitation wavelengths and samples a complete optical spectrum for each, yielding an excitation-emission matrix (EEM). Upon study of the EEM, it is possible to determine the presence of multiple optical contrast agents since these dyes can have characteristic spectra that can be separated. Here, we demonstrate EES specifically designed for use in conjunction with MR. This EES is applied with an in-suite control setup that permits real-time navigation, utilizing active MR tracking catheters, and providing a platform for MR-guided tissue characterization. The EES system is used in a demonstration experiment to highlight MR imaging, MR guidance in conjunction with a catheter-based optical measurement.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6918
DOIs
StatePublished - 2008
Externally publishedYes
EventMedical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling - San Diego, CA, United States
Duration: Feb 17 2008Feb 19 2008

Other

OtherMedical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling
CountryUnited States
CitySan Diego, CA
Period2/17/082/19/08

Fingerprint

Optical emission spectroscopy
Catheters
Emission spectroscopy
Tissue
Navigation
Demonstrations
Dyes
Imaging techniques
Wavelength
Experiments

Keywords

  • Excitation-emission spectroscopy
  • In vivo tissue characterization
  • MR guidance
  • MR-guided tissue characterization
  • Tissue characterization

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Herzka, D., Kotys, M. S., Krueger, S., Traughber, B. J., Heroux, J., Gharib, A. M., ... Wood, B. J. (2008). MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6918). [69181U] https://doi.org/10.1117/12.770758

MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. / Herzka, Daniel; Kotys, M. S.; Krueger, S.; Traughber, B. J.; Heroux, J.; Gharib, A. M.; Ohayon, J.; Weiss, S.; Pettigrew, R. I.; Wood, B. J.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6918 2008. 69181U.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Herzka, D, Kotys, MS, Krueger, S, Traughber, BJ, Heroux, J, Gharib, AM, Ohayon, J, Weiss, S, Pettigrew, RI & Wood, BJ 2008, MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6918, 69181U, Medical Imaging 2008 - Visualization, Image-Guided Procedures, and Modeling, San Diego, CA, United States, 2/17/08. https://doi.org/10.1117/12.770758
Herzka D, Kotys MS, Krueger S, Traughber BJ, Heroux J, Gharib AM et al. MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6918. 2008. 69181U https://doi.org/10.1117/12.770758
Herzka, Daniel ; Kotys, M. S. ; Krueger, S. ; Traughber, B. J. ; Heroux, J. ; Gharib, A. M. ; Ohayon, J. ; Weiss, S. ; Pettigrew, R. I. ; Wood, B. J. / MR-guided catheter-based excitation emission optical spectroscopy for in vivo tissue characterization. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6918 2008.
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