MR-based attenuation correction for whole-body PET/MR system

Z. Hu, S. Renisch, B. Schweizer, T. Blaffert, N. Ojha, T. Guo, J. Tang, C. Tung, J. Kaste, V. Schulz, I. Torres, L. Shao

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Philips has introduced the world's first whole body sequential PET/MR system. We present the current status of MR-based attenuation correction (MRAC) technique. MRAC consists of MR image acquisition, segmentation, truncation compensation (TC), -value assignment, as well as correction for patient table and RF coils. These components have been described last year; this paper focuses on updates of the two most critical steps of MRAC: segmentation and TC. The segmentation algorithm attempts to distinguish 3 biological classes: air, lungs, and soft tissue. It combines an intensity-based region-growing technique with lung-model adaptation. For TC, the following three-step approach to correct for truncation in the MR-based attenuation maps has been developed and investigated: (A) Areas in the attenuation map which are possibly truncated are identified. (B) For these areas, an estimate of the outer patient contour is extracted from a registered PET image which is reconstructed without attenuation correction. (C) Truncation correction areas as extracted from the PET contours are added to attenuation map. The segmentation algorithm was applied to a number of datasets from a large pool of volunteers from multiple MR systems. The algorithm yields expected results except for susceptibility and motion artifacts. While the truncation compensation algorithm works for most cases, the robustness needs to be further improved.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposuim and Medical Imaging Conference, NSS/MIC 2010
Pages2119-2122
Number of pages4
DOIs
StatePublished - Dec 1 2010
Event2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010 - Knoxville, TN, United States
Duration: Oct 30 2010Nov 6 2010

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Other

Other2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010
CountryUnited States
CityKnoxville, TN
Period10/30/1011/6/10

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Hu, Z., Renisch, S., Schweizer, B., Blaffert, T., Ojha, N., Guo, T., Tang, J., Tung, C., Kaste, J., Schulz, V., Torres, I., & Shao, L. (2010). MR-based attenuation correction for whole-body PET/MR system. In IEEE Nuclear Science Symposuim and Medical Imaging Conference, NSS/MIC 2010 (pp. 2119-2122). [5874153] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2010.5874153