Moving forward: Mechanisms of chemoattractant gradient sensing

Jonathan Franca-Koh, Peter N Devreotes

Research output: Contribution to journalArticle

Abstract

Cells use an internal compass to sense the direction of chemoattractant gradients. This is used to bias pseudopod extension at the front of the cell and to orient cell polarization. Recent studies have highlighted the important roles played by phosphoinositide-3,4,5-triphosphate and small G proteins, but many questions remain.

Original languageEnglish (US)
Pages (from-to)300-308
Number of pages9
JournalPhysiology
Volume19
Issue number5
StatePublished - Oct 2004

Fingerprint

Chemotactic Factors
Pseudopodia
Monomeric GTP-Binding Proteins

ASJC Scopus subject areas

  • Physiology

Cite this

Moving forward : Mechanisms of chemoattractant gradient sensing. / Franca-Koh, Jonathan; Devreotes, Peter N.

In: Physiology, Vol. 19, No. 5, 10.2004, p. 300-308.

Research output: Contribution to journalArticle

Franca-Koh, Jonathan ; Devreotes, Peter N. / Moving forward : Mechanisms of chemoattractant gradient sensing. In: Physiology. 2004 ; Vol. 19, No. 5. pp. 300-308.
@article{4356f2c58c4a40748ed94cbc19923f02,
title = "Moving forward: Mechanisms of chemoattractant gradient sensing",
abstract = "Cells use an internal compass to sense the direction of chemoattractant gradients. This is used to bias pseudopod extension at the front of the cell and to orient cell polarization. Recent studies have highlighted the important roles played by phosphoinositide-3,4,5-triphosphate and small G proteins, but many questions remain.",
author = "Jonathan Franca-Koh and Devreotes, {Peter N}",
year = "2004",
month = "10",
language = "English (US)",
volume = "19",
pages = "300--308",
journal = "Physiology",
issn = "1548-9213",
publisher = "American Physiological Society",
number = "5",

}

TY - JOUR

T1 - Moving forward

T2 - Mechanisms of chemoattractant gradient sensing

AU - Franca-Koh, Jonathan

AU - Devreotes, Peter N

PY - 2004/10

Y1 - 2004/10

N2 - Cells use an internal compass to sense the direction of chemoattractant gradients. This is used to bias pseudopod extension at the front of the cell and to orient cell polarization. Recent studies have highlighted the important roles played by phosphoinositide-3,4,5-triphosphate and small G proteins, but many questions remain.

AB - Cells use an internal compass to sense the direction of chemoattractant gradients. This is used to bias pseudopod extension at the front of the cell and to orient cell polarization. Recent studies have highlighted the important roles played by phosphoinositide-3,4,5-triphosphate and small G proteins, but many questions remain.

UR - http://www.scopus.com/inward/record.url?scp=8144224377&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=8144224377&partnerID=8YFLogxK

M3 - Article

C2 - 15381759

AN - SCOPUS:8144224377

VL - 19

SP - 300

EP - 308

JO - Physiology

JF - Physiology

SN - 1548-9213

IS - 5

ER -