TY - JOUR
T1 - Motor extinction in distinct reference frames
T2 - A double dissociation
AU - Heidler-Gary, Jennifer
AU - Pawlak, Mikolaj
AU - Herskovits, Edward H.
AU - Newhart, Melissa
AU - Davis, Cameron
AU - Trupe, Lydia A.
AU - Hillis, Argye E.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - Objective: Test the hypothesis that right hemisphere stroke can cause extinction of left hand movements or movements of either hand held in left space, when both are used simultaneously, possibly depending on lesion site. Methods: 93 non-hemiplegic patients with acute right hemisphere stroke were tested for motor extinction by pressing a counter rapidly for one minute with the right hand, left hand, or both simultaneously with their hands held at their sides, or crossed over midline. Results: We identified two distinct types of motor extinction in separate patients; 20 patients extinguished left hand movements held in left or right space (left canonical body extinction); the most significantly associated voxel cluster of ischemic tissue was in the right temporal white matter. Seven patients extinguished either hand held in left space (left space extinction), and the most significantly associated voxel cluster of ischemic tissue was in right parietal white matter. Conclusions: There was a double dissociation between left canonical body extinction and left space motor extinction. Left canonical body extinction seems to be associated with more dorsal (parietal) ischemia, and left canonical body extinction seems to be associated with more ventral (temporal) ischemia.
AB - Objective: Test the hypothesis that right hemisphere stroke can cause extinction of left hand movements or movements of either hand held in left space, when both are used simultaneously, possibly depending on lesion site. Methods: 93 non-hemiplegic patients with acute right hemisphere stroke were tested for motor extinction by pressing a counter rapidly for one minute with the right hand, left hand, or both simultaneously with their hands held at their sides, or crossed over midline. Results: We identified two distinct types of motor extinction in separate patients; 20 patients extinguished left hand movements held in left or right space (left canonical body extinction); the most significantly associated voxel cluster of ischemic tissue was in the right temporal white matter. Seven patients extinguished either hand held in left space (left space extinction), and the most significantly associated voxel cluster of ischemic tissue was in right parietal white matter. Conclusions: There was a double dissociation between left canonical body extinction and left space motor extinction. Left canonical body extinction seems to be associated with more dorsal (parietal) ischemia, and left canonical body extinction seems to be associated with more ventral (temporal) ischemia.
KW - Extinction
KW - bimanual motor
KW - left body
KW - left space
UR - http://www.scopus.com/inward/record.url?scp=84872471859&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872471859&partnerID=8YFLogxK
U2 - 10.3233/BEN-2012-110254
DO - 10.3233/BEN-2012-110254
M3 - Article
C2 - 22713397
AN - SCOPUS:84872471859
VL - 26
SP - 111
EP - 119
JO - Behavioural Neurology
JF - Behavioural Neurology
SN - 0953-4180
IS - 1-2
ER -