Motion-compensated optical coherence tomography based on higher-order regression for real-time volumetric imaging

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optical Coherence Tomography (OCT) has evolved into a powerful clinical tool, with a wide range of applications in ophthalmology. However, most OCT systems for real-time volumetric (3D) and in vivo imaging suffer from image distortion due to motion artifacts induced by involuntary and physiological movements of the living tissue. Several methods have been proposed to obtain motion-free images, yet they are generally limited in their applicability due to long acquisition times, requiring multiple volumes [1], and/or the need for additional hardware [2]. Here we propose and analyze a motion-compensated 3D-OCT imaging system that uses a higher-order regression analysis and show that it can effectively correct the motion artifacts within 0 to 5 Hz in real time without requiring additional hardware.

Original languageEnglish (US)
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV
EditorsJoseph A. Izatt, James G. Fujimoto
PublisherSPIE
ISBN (Electronic)9781510640955
DOIs
StatePublished - 2021
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV 2021 - Virtual, Online, United States
Duration: Mar 6 2021Mar 11 2021

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11630
ISSN (Print)1605-7422

Conference

ConferenceOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV 2021
Country/TerritoryUnited States
CityVirtual, Online
Period3/6/213/11/21

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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