Motility abnormality in intestinal atresia

Edward J. Doolin, Herbert S. Ormsbee, J. Laurance Hill

Research output: Contribution to journalArticle

Abstract

This study was designed to investigate the motility of the small bowel of the lamb under the conditions of experimental intestinal atresia. Of 26 fetal lambs operated upon (50 to 90 days gestation), 13 came to term. All term lambs exhibited a type 3a atresia. Six were successfully repaired and had intestinal myoelectric activity monitored for periods from 2 to 27 hours. A slow wave pattern (12 to 13/min) was present in the bowel of control lambs and in the proximal dilated bowel and the microbowel of atretic lambs, confirming the presence of functional smooth muscle. Spike potentials, which indicated circular muscular contractions, occurred 10% of the time in the control intestine, 5% in the proximal dilated gut (P

Original languageEnglish (US)
Pages (from-to)320-324
Number of pages5
JournalJournal of Pediatric Surgery
Volume22
Issue number4
DOIs
StatePublished - 1987
Externally publishedYes

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Intestinal Atresia
Muscle Contraction
Action Potentials
Intestines
Smooth Muscle
Pregnancy

Keywords

  • Intestinal atresia
  • intestinal motility

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Doolin, E. J., Ormsbee, H. S., & Laurance Hill, J. (1987). Motility abnormality in intestinal atresia. Journal of Pediatric Surgery, 22(4), 320-324. https://doi.org/10.1016/S0022-3468(87)80233-6

Motility abnormality in intestinal atresia. / Doolin, Edward J.; Ormsbee, Herbert S.; Laurance Hill, J.

In: Journal of Pediatric Surgery, Vol. 22, No. 4, 1987, p. 320-324.

Research output: Contribution to journalArticle

Doolin, EJ, Ormsbee, HS & Laurance Hill, J 1987, 'Motility abnormality in intestinal atresia', Journal of Pediatric Surgery, vol. 22, no. 4, pp. 320-324. https://doi.org/10.1016/S0022-3468(87)80233-6
Doolin, Edward J. ; Ormsbee, Herbert S. ; Laurance Hill, J. / Motility abnormality in intestinal atresia. In: Journal of Pediatric Surgery. 1987 ; Vol. 22, No. 4. pp. 320-324.
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