Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines

Mengdi Xu, Shengnan Lyu, Yingtian Xu, Can Kocabalkanli, Brian K. Chirikjian, John S. Chirikjian, Joshua Davis, Jin Seob Kim, Iulian Iordachita, Russell H Taylor, Gregory S. Chirikjian

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper describes the design of a fully automated apparatus to dispense mosquitoes into isolate units. This automation system consists of several process units including (1) facilitating the water vortex with a fan-shape rotor to gently transport the mosquitoes to the sorting slides with a conical geometry, (2) exploiting slides to guide mosquitoes to turntables driven by gears one by one, and (3) reorienting the mosquito until its proboscis points outward along the radial direction of the cone, aided by computer vision. This automation system serves as the first processing stage for collecting mosquito salivary glands. The sporozoites contained in the mosquito glands are the source material to produce Sanaria's first generation PfSPZ vaccines. The Mosquito Staging System can dramatically enhance the mass production of Malaria Vaccine which is essential to prevent the propagation of Malaria.

Original languageEnglish (US)
Title of host publication2019 IEEE 15th International Conference on Automation Science and Engineering, CASE 2019
PublisherIEEE Computer Society
Pages443-449
Number of pages7
ISBN (Electronic)9781728103556
DOIs
StatePublished - Aug 1 2019
Event15th IEEE International Conference on Automation Science and Engineering, CASE 2019 - Vancouver, Canada
Duration: Aug 22 2019Aug 26 2019

Publication series

NameIEEE International Conference on Automation Science and Engineering
Volume2019-August
ISSN (Print)2161-8070
ISSN (Electronic)2161-8089

Conference

Conference15th IEEE International Conference on Automation Science and Engineering, CASE 2019
CountryCanada
CityVancouver
Period8/22/198/26/19

Fingerprint

Vaccines
Automation
Phonographs
Sorting
Computer vision
Fans
Gears
Cones
Chemical reactions
Vortex flow
Rotors
Geometry
Processing
Water

Keywords

  • Automation
  • Design
  • Malaria Vaccine
  • Medical Robot

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Electrical and Electronic Engineering

Cite this

Xu, M., Lyu, S., Xu, Y., Kocabalkanli, C., Chirikjian, B. K., Chirikjian, J. S., ... Chirikjian, G. S. (2019). Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines. In 2019 IEEE 15th International Conference on Automation Science and Engineering, CASE 2019 (pp. 443-449). [8843147] (IEEE International Conference on Automation Science and Engineering; Vol. 2019-August). IEEE Computer Society. https://doi.org/10.1109/COASE.2019.8843147

Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines. / Xu, Mengdi; Lyu, Shengnan; Xu, Yingtian; Kocabalkanli, Can; Chirikjian, Brian K.; Chirikjian, John S.; Davis, Joshua; Kim, Jin Seob; Iordachita, Iulian; Taylor, Russell H; Chirikjian, Gregory S.

2019 IEEE 15th International Conference on Automation Science and Engineering, CASE 2019. IEEE Computer Society, 2019. p. 443-449 8843147 (IEEE International Conference on Automation Science and Engineering; Vol. 2019-August).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Xu, M, Lyu, S, Xu, Y, Kocabalkanli, C, Chirikjian, BK, Chirikjian, JS, Davis, J, Kim, JS, Iordachita, I, Taylor, RH & Chirikjian, GS 2019, Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines. in 2019 IEEE 15th International Conference on Automation Science and Engineering, CASE 2019., 8843147, IEEE International Conference on Automation Science and Engineering, vol. 2019-August, IEEE Computer Society, pp. 443-449, 15th IEEE International Conference on Automation Science and Engineering, CASE 2019, Vancouver, Canada, 8/22/19. https://doi.org/10.1109/COASE.2019.8843147
Xu M, Lyu S, Xu Y, Kocabalkanli C, Chirikjian BK, Chirikjian JS et al. Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines. In 2019 IEEE 15th International Conference on Automation Science and Engineering, CASE 2019. IEEE Computer Society. 2019. p. 443-449. 8843147. (IEEE International Conference on Automation Science and Engineering). https://doi.org/10.1109/COASE.2019.8843147
Xu, Mengdi ; Lyu, Shengnan ; Xu, Yingtian ; Kocabalkanli, Can ; Chirikjian, Brian K. ; Chirikjian, John S. ; Davis, Joshua ; Kim, Jin Seob ; Iordachita, Iulian ; Taylor, Russell H ; Chirikjian, Gregory S. / Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines. 2019 IEEE 15th International Conference on Automation Science and Engineering, CASE 2019. IEEE Computer Society, 2019. pp. 443-449 (IEEE International Conference on Automation Science and Engineering).
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