Mosquito Microbiota and Implications for Disease Control

Han Gao; Chunlai Cui; Lili Wang; Marcelo Jacobs-Lorena; Sibao Wang

doi:10.1016/j.pt.2019.12.001

Mosquito Microbiota and Implications for Disease Control

Han Gao, Chunlai Cui, Lili Wang, Marcelo Jacobs-Lorena, Sibao Wang

Bloomberg School of Public Health

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these pathogens in the mosquito vector before they are transmitted to humans is an effective strategy to prevent mosquito-borne diseases. Like most higher organisms, mosquitoes harbor a highly diverse and dynamic microbial flora that can be explored for prevention of pathogen transmission. Here we review the structure and function of the mosquito microbiota, including bacteria, fungi, and viruses, and discuss the potential of using components of the microbiota to thwart pathogen transmission.

Original language	English (US)
Pages (from-to)	98-111
Number of pages	14
Journal	Trends in parasitology
Volume	36
Issue number	2
DOIs	https://doi.org/10.1016/j.pt.2019.12.001
State	Published - Feb 2020

Keywords

microbiota
mosquito
transmission
vector-borne diseases

ASJC Scopus subject areas

Parasitology
Infectious Diseases

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10.1016/j.pt.2019.12.001

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title = "Mosquito Microbiota and Implications for Disease Control",

abstract = "Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these pathogens in the mosquito vector before they are transmitted to humans is an effective strategy to prevent mosquito-borne diseases. Like most higher organisms, mosquitoes harbor a highly diverse and dynamic microbial flora that can be explored for prevention of pathogen transmission. Here we review the structure and function of the mosquito microbiota, including bacteria, fungi, and viruses, and discuss the potential of using components of the microbiota to thwart pathogen transmission.",

keywords = "microbiota, mosquito, transmission, vector-borne diseases",

author = "Han Gao and Chunlai Cui and Lili Wang and Marcelo Jacobs-Lorena and Sibao Wang",

note = "Funding Information: This work was supported by grants from the National Natural Science Foundation of China (grants 31830086, 31772534, 31830086, 31472044), the National Key R&D Program of China (2017YFD0200400, 2018YFA0900502), the Strategic Priority Research Program of Chinese Academy of Sciences (grant XDB11010500), the Key Research Program of the Chinese Academy of Sciences (KFZD-SW-219), National Institutes of Health (NIH) grant R01AI031478, and the Bloomberg Philanthropies. Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2020",

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doi = "10.1016/j.pt.2019.12.001",

language = "English (US)",

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AU - Gao, Han

AU - Cui, Chunlai

AU - Wang, Lili

AU - Jacobs-Lorena, Marcelo

AU - Wang, Sibao

N1 - Funding Information: This work was supported by grants from the National Natural Science Foundation of China (grants 31830086, 31772534, 31830086, 31472044), the National Key R&D Program of China (2017YFD0200400, 2018YFA0900502), the Strategic Priority Research Program of Chinese Academy of Sciences (grant XDB11010500), the Key Research Program of the Chinese Academy of Sciences (KFZD-SW-219), National Institutes of Health (NIH) grant R01AI031478, and the Bloomberg Philanthropies. Publisher Copyright: © 2019 Elsevier Ltd

PY - 2020/2

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N2 - Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these pathogens in the mosquito vector before they are transmitted to humans is an effective strategy to prevent mosquito-borne diseases. Like most higher organisms, mosquitoes harbor a highly diverse and dynamic microbial flora that can be explored for prevention of pathogen transmission. Here we review the structure and function of the mosquito microbiota, including bacteria, fungi, and viruses, and discuss the potential of using components of the microbiota to thwart pathogen transmission.

AB - Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these pathogens in the mosquito vector before they are transmitted to humans is an effective strategy to prevent mosquito-borne diseases. Like most higher organisms, mosquitoes harbor a highly diverse and dynamic microbial flora that can be explored for prevention of pathogen transmission. Here we review the structure and function of the mosquito microbiota, including bacteria, fungi, and viruses, and discuss the potential of using components of the microbiota to thwart pathogen transmission.

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KW - transmission

KW - vector-borne diseases

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Mosquito Microbiota and Implications for Disease Control

Abstract

Keywords

ASJC Scopus subject areas

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