Mortality Surveillance Methods to Identify and Characterize Deaths in Child Health and Mortality Prevention Surveillance Network Sites

Navit T. Salzberg, Kasthuri Sivalogan, Quique Bassat, Allan W. Taylor, Sunday Adedini, Shams El Arifeen, Nega Assefa, Dianna M. Blau, Richard Chawana, Carrie Jo Cain, Kevin P. Cain, J. Patrick Caneer, Mischka Garel, Emily S. Gurley, Reinhard Kaiser, Karen L. Kotloff, Inacio Mandomando, Timothy Morris, Peter Nyamthimba Onyango, Hossain M.S. SazzadJ. Anthony G. Scott, Anna C. Seale, Antonio Sitoe, Samba O. Sow, Milagritos D. Tapia, Ellen A. Whitney, Mary Claire Worrell, Emily Zielinski-Gutierrez, Shabir A. Madhi, Pratima L. Raghunathan, Jeffrey P. Koplan, Robert F. Breiman, Janet Agaya, Victor Akelo, Beth A. Tippett Barr, Sanwarul Bari, Farzana Islam, Afruna Rahman, Yadeta Dessie, Letta Gedefa, Erick Kaluma, Adama Mamby Keita, Uma U. Onwuchekwa, Diakaridia Sidibe, Amara Jambai, Lola Madrid, Stefanie Wittmann, Ashka Mehta, Khátia Munguambe, Ariel Nhacolo, Pio Vitorino, Charfudin Sacoor, Jessica Preslar, Dickens Onyango, Jaume Ordi, Clara Menéndez Santos, Solomon Samura, Megan Turk, Rosauro Varo

Research output: Contribution to journalArticle

Abstract

Despite reductions over the past 2 decades, childhood mortality remains high in low- and middle-income countries in sub-Saharan Africa and South Asia. In these settings, children often die at home, without contact with the health system, and are neither accounted for, nor attributed with a cause of death. In addition, when cause of death determinations occur, they often use nonspecific methods. Consequently, findings from models currently utilized to build national and global estimates of causes of death are associated with substantial uncertainty. Higher-quality data would enable stakeholders to effectively target interventions for the leading causes of childhood mortality, a critical component to achieving the Sustainable Development Goals by eliminating preventable perinatal and childhood deaths. The Child Health and Mortality Prevention Surveillance (CHAMPS) Network tracks the causes of under-5 mortality and stillbirths at sites in sub-Saharan Africa and South Asia through comprehensive mortality surveillance, utilizing minimally invasive tissue sampling (MITS), postmortem laboratory and pathology testing, verbal autopsy, and clinical and demographic data. CHAMPS sites have established facility- and community-based mortality notification systems, which aim to report potentially eligible deaths, defined as under-5 deaths and stillbirths within a defined catchment area, within 24-36 hours so that MITS can be conducted quickly after death. Where MITS has been conducted, a final cause of death is determined by an expert review panel. Data on cause of death will be provided to local, national, and global stakeholders to inform strategies to reduce perinatal and childhood mortality in sub-Saharan Africa and South Asia.

Original languageEnglish (US)
Pages (from-to)S262-S273
JournalClinical Infectious Diseases
Volume69
DOIs
StatePublished - Oct 15 2019

Keywords

  • CHAMPS
  • child mortality
  • global health
  • surveillance

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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    Salzberg, N. T., Sivalogan, K., Bassat, Q., Taylor, A. W., Adedini, S., El Arifeen, S., Assefa, N., Blau, D. M., Chawana, R., Cain, C. J., Cain, K. P., Caneer, J. P., Garel, M., Gurley, E. S., Kaiser, R., Kotloff, K. L., Mandomando, I., Morris, T., Nyamthimba Onyango, P., ... Varo, R. (2019). Mortality Surveillance Methods to Identify and Characterize Deaths in Child Health and Mortality Prevention Surveillance Network Sites. Clinical Infectious Diseases, 69, S262-S273. https://doi.org/10.1093/cid/ciz599