Abstract
Background: Delays in the release of national vital statistics hinder timely assessment of influenza severity, especially during pandemics. Inpatient mortality records could provide timelier estimates of influenza-associated mortality. Methods: We compiled weekly age-specific deaths for various causes from US State Inpatient Databases (1990-2010) and national vital statistics (1990-2009). We calculated influenza-attributable excess deaths by season based on Poisson regression models driven by indicators of respiratory virus activity, seasonality, and temporal trends. Results: Extrapolations of excess mortality from inpatient data fell within 11% and 17% of vital statistics estimates for pandemic and seasonal influenza, respectively, with high year-to-year correlation (Spearman's rho = 0·87-0·90, P
| Original language | English (US) |
|---|---|
| Pages (from-to) | 863-871 |
| Number of pages | 9 |
| Journal | Influenza and other Respiratory Viruses |
| Volume | 7 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 2013 |
| Externally published | Yes |
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Keywords
- Age patterns
- Influenza
- Influenza-related mortality
- Pandemic influenza
- Years of life lost
ASJC Scopus subject areas
- Infectious Diseases
- Pulmonary and Respiratory Medicine
- Public Health, Environmental and Occupational Health
- Epidemiology
Cite this
Mortality burden of the 2009-10 influenza pandemic in the United States : Improving the timeliness of influenza severity estimates using inpatient mortality records. / Charu, Vivek; Simonsen, Lone; Lustig, Roger; Steiner, Claudia Angelica; Viboud, Cécile.
In: Influenza and other Respiratory Viruses, Vol. 7, No. 5, 09.2013, p. 863-871.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mortality burden of the 2009-10 influenza pandemic in the United States
T2 - Improving the timeliness of influenza severity estimates using inpatient mortality records
AU - Charu, Vivek
AU - Simonsen, Lone
AU - Lustig, Roger
AU - Steiner, Claudia Angelica
AU - Viboud, Cécile
PY - 2013/9
Y1 - 2013/9
N2 - Background: Delays in the release of national vital statistics hinder timely assessment of influenza severity, especially during pandemics. Inpatient mortality records could provide timelier estimates of influenza-associated mortality. Methods: We compiled weekly age-specific deaths for various causes from US State Inpatient Databases (1990-2010) and national vital statistics (1990-2009). We calculated influenza-attributable excess deaths by season based on Poisson regression models driven by indicators of respiratory virus activity, seasonality, and temporal trends. Results: Extrapolations of excess mortality from inpatient data fell within 11% and 17% of vital statistics estimates for pandemic and seasonal influenza, respectively, with high year-to-year correlation (Spearman's rho = 0·87-0·90, P
AB - Background: Delays in the release of national vital statistics hinder timely assessment of influenza severity, especially during pandemics. Inpatient mortality records could provide timelier estimates of influenza-associated mortality. Methods: We compiled weekly age-specific deaths for various causes from US State Inpatient Databases (1990-2010) and national vital statistics (1990-2009). We calculated influenza-attributable excess deaths by season based on Poisson regression models driven by indicators of respiratory virus activity, seasonality, and temporal trends. Results: Extrapolations of excess mortality from inpatient data fell within 11% and 17% of vital statistics estimates for pandemic and seasonal influenza, respectively, with high year-to-year correlation (Spearman's rho = 0·87-0·90, P
KW - Age patterns
KW - Influenza
KW - Influenza-related mortality
KW - Pandemic influenza
KW - Years of life lost
UR - http://www.scopus.com/inward/record.url?scp=84882702911&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84882702911&partnerID=8YFLogxK
U2 - 10.1111/irv.12096
DO - 10.1111/irv.12096
M3 - Article
C2 - 23419002
AN - SCOPUS:84882702911
VL - 7
SP - 863
EP - 871
JO - Influenza and other Respiratory Viruses
JF - Influenza and other Respiratory Viruses
SN - 1750-2640
IS - 5
ER -