Mortality burden of the 2009-10 influenza pandemic in the United States: Improving the timeliness of influenza severity estimates using inpatient mortality records

Vivek Charu, Lone Simonsen, Roger Lustig, Claudia Angelica Steiner, Cécile Viboud

Research output: Contribution to journalArticle

Abstract

Background: Delays in the release of national vital statistics hinder timely assessment of influenza severity, especially during pandemics. Inpatient mortality records could provide timelier estimates of influenza-associated mortality. Methods: We compiled weekly age-specific deaths for various causes from US State Inpatient Databases (1990-2010) and national vital statistics (1990-2009). We calculated influenza-attributable excess deaths by season based on Poisson regression models driven by indicators of respiratory virus activity, seasonality, and temporal trends. Results: Extrapolations of excess mortality from inpatient data fell within 11% and 17% of vital statistics estimates for pandemic and seasonal influenza, respectively, with high year-to-year correlation (Spearman's rho = 0·87-0·90, P 

Original languageEnglish (US)
Pages (from-to)863-871
Number of pages9
JournalInfluenza and other Respiratory Viruses
Volume7
Issue number5
DOIs
StatePublished - Sep 2013
Externally publishedYes

Fingerprint

Pandemics
Vital Statistics
Human Influenza
Inpatients
Mortality
Cause of Death
Databases
Viruses

Keywords

  • Age patterns
  • Influenza
  • Influenza-related mortality
  • Pandemic influenza
  • Years of life lost

ASJC Scopus subject areas

  • Infectious Diseases
  • Pulmonary and Respiratory Medicine
  • Public Health, Environmental and Occupational Health
  • Epidemiology

Cite this

Mortality burden of the 2009-10 influenza pandemic in the United States : Improving the timeliness of influenza severity estimates using inpatient mortality records. / Charu, Vivek; Simonsen, Lone; Lustig, Roger; Steiner, Claudia Angelica; Viboud, Cécile.

In: Influenza and other Respiratory Viruses, Vol. 7, No. 5, 09.2013, p. 863-871.

Research output: Contribution to journalArticle

Charu, Vivek ; Simonsen, Lone ; Lustig, Roger ; Steiner, Claudia Angelica ; Viboud, Cécile. / Mortality burden of the 2009-10 influenza pandemic in the United States : Improving the timeliness of influenza severity estimates using inpatient mortality records. In: Influenza and other Respiratory Viruses. 2013 ; Vol. 7, No. 5. pp. 863-871.
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