Morphometry of the amygdala in schizophrenia and psychotic bipolar disorder

Pamela B. Mahon, David S. Lee, Huong Trinh, Daniel Tward, Michael I. Miller, Laurent Younes, Patrick Ernest Barta, J. Tilak Ratnanather

Research output: Contribution to journalArticle

Abstract

Volumetric studies suggest smaller amygdalae in subjects with schizophrenia (SZ) than with bipolar disorder (BP). We use morphometry to identify subregions of amygdala differentially affected in SZ and psychotic BP. Based on template centered population analysis, the shape of the amygdala in psychotic BP differs from SZ (pleft=0.044, pright=0.042). Using a high-field 7T atlas, the bilateral basolateral, basomedial and centromedial subregions and the right lateral subregion were significantly atrophied in SZ compared to psychotic BP (p

Original languageEnglish (US)
Pages (from-to)199-202
Number of pages4
JournalSchizophrenia Research
Volume164
Issue number1-3
DOIs
StatePublished - May 1 2015

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Keywords

  • Amygdala
  • Morphometry
  • Psychotic bipolar disorder
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Mahon, P. B., Lee, D. S., Trinh, H., Tward, D., Miller, M. I., Younes, L., Barta, P. E., & Ratnanather, J. T. (2015). Morphometry of the amygdala in schizophrenia and psychotic bipolar disorder. Schizophrenia Research, 164(1-3), 199-202. https://doi.org/10.1016/j.schres.2015.02.011