Abstract
Volumetric studies suggest smaller amygdalae in subjects with schizophrenia (SZ) than with bipolar disorder (BP). We use morphometry to identify subregions of amygdala differentially affected in SZ and psychotic BP. Based on template centered population analysis, the shape of the amygdala in psychotic BP differs from SZ (pleft=0.044, pright=0.042). Using a high-field 7T atlas, the bilateral basolateral, basomedial and centromedial subregions and the right lateral subregion were significantly atrophied in SZ compared to psychotic BP (p<0.02). These results suggest that change in shape of amygdala may represent a morphologic feature distinguishing SZ from psychotic BP.
Original language | English (US) |
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Pages (from-to) | 199-202 |
Number of pages | 4 |
Journal | Schizophrenia Research |
Volume | 164 |
Issue number | 1-3 |
DOIs | |
State | Published - May 1 2015 |
Keywords
- Amygdala
- Morphometry
- Psychotic bipolar disorder
- Schizophrenia
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry