TY - GEN
T1 - Morphological image denoising and random-walks spot detection in microarry images
AU - Mastrogianni, A.
AU - Dermatas, E.
AU - Bezerianos, A.
PY - 2010
Y1 - 2010
N2 - In this paper, a novel method for noise reduction and spot detection in microarray images, based on mathematical morphology and Random-Walks model is presented and evaluated. Initially, an automatic method detects the subarrays and a morphological denoising method is used to reduce artifacts at each individual subarray. In the enhanced images, a novel segmentation algorithm based on Random-Walker algorithm (RWA) derives the spot positions. The proposed method is validated in two different databases of real distorted microarray images, giving quite satisfying results both in noise elimination and spot detection accuracy.
AB - In this paper, a novel method for noise reduction and spot detection in microarray images, based on mathematical morphology and Random-Walks model is presented and evaluated. Initially, an automatic method detects the subarrays and a morphological denoising method is used to reduce artifacts at each individual subarray. In the enhanced images, a novel segmentation algorithm based on Random-Walker algorithm (RWA) derives the spot positions. The proposed method is validated in two different databases of real distorted microarray images, giving quite satisfying results both in noise elimination and spot detection accuracy.
UR - http://www.scopus.com/inward/record.url?scp=84903835188&partnerID=8YFLogxK
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U2 - 10.1142/9789814322034_0015
DO - 10.1142/9789814322034_0015
M3 - Conference contribution
AN - SCOPUS:84903835188
SN - 9814322024
SN - 9789814322027
T3 - Proceedings of the 9th International Workshop on Mathematical Methods in Scattering Theory and Biomedical Engineering: Advanced Topics in Scattering and Biomedical Engineering
SP - 143
EP - 150
BT - Proceedings of the 9th International Workshop on Mathematical Methods in Scattering Theory and Biomedical Engineering
PB - World Scientific Publishing Co. Pte Ltd
T2 - 2009 9th International Workshop on Mathematical Methods in Scattering Theory and Biomedical Engineering
Y2 - 9 October 2009 through 11 October 2009
ER -