Morphologic basis of MR imaging of benign prostatic hyperplasia

Ralph H Hruban, Elias Zerhouni, Azar P. Dagher, Marc L. Pessar, Grover M. Hutchins

Research output: Contribution to journalArticle

Abstract

Fifteen prostates were obtained from patients autopsied at The Johns Hopkins Hospital and imaged fresh in vitro by high resolution magnetic resonance (MR) imaging with a surface coil. Following scanning, the specimens were fixed and sectioned in the same plane as the MR images. The prostate sections, corresponding to the MR images, were examined grossly and histologically for prostate pathology. Tissue characteristics were quantified by morphometric techniques and correlated with MR image intensity. Five prostates were normal and showed two distinct anatomic zones, a central periurethral zone and a peripheral zone. These two zones corresponded to two zones identified on MR of the five normal prostates. In contrast, both the MR images and the pathologic and morphometric studies of nine of the 10 prostates with benign prostatic hyperplasia (BPH) showed three distinct zones: A central region of BPH, a surrounding fibrous capsule, and a peripheral zone. This study suggests that there is a morphologic basis for MR intensity in the prostate.

Original languageEnglish (US)
Pages (from-to)1035-1041
Number of pages7
JournalJournal of Computer Assisted Tomography
Volume11
Issue number6
StatePublished - 1987

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Prostatic Hyperplasia
Prostate
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Capsules
Pathology

Keywords

  • Magnetic resonance imaging
  • Prostate, abnormalities
  • Prostate, anatomy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Morphologic basis of MR imaging of benign prostatic hyperplasia. / Hruban, Ralph H; Zerhouni, Elias; Dagher, Azar P.; Pessar, Marc L.; Hutchins, Grover M.

In: Journal of Computer Assisted Tomography, Vol. 11, No. 6, 1987, p. 1035-1041.

Research output: Contribution to journalArticle

Hruban, Ralph H ; Zerhouni, Elias ; Dagher, Azar P. ; Pessar, Marc L. ; Hutchins, Grover M. / Morphologic basis of MR imaging of benign prostatic hyperplasia. In: Journal of Computer Assisted Tomography. 1987 ; Vol. 11, No. 6. pp. 1035-1041.
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