TY - JOUR
T1 - More fat and fewer seizures
T2 - Dietary therapies for epilepsy
AU - Kossoff, Eric H.
PY - 2004/7/1
Y1 - 2004/7/1
N2 - The ketogenic diet is a high-fat, adequate protein, low carbohydrate diet that has been used for the treatment of intractable childhood epilepsy since the 1920s. The diet mimics the biochemical changes associated with starvation, which create ketosis. Although less commonly used in later decades because of the increased availability of anticonvulsants, the ketogenic diet has re-emerged as a therapeutic option. Only a decade ago the ketogenic diet was seen as a last resort; however, it has become more commonly used in academic centres throughout the world even early in the course of epilepsy. The Atkins diet is a recently used, less restrictive, therapy that also creates ketosis and can lower the number of seizures. Dietary therapies may become even more valuable in the therapy of epilepsy when the mechanisms underlying their success are understood.
AB - The ketogenic diet is a high-fat, adequate protein, low carbohydrate diet that has been used for the treatment of intractable childhood epilepsy since the 1920s. The diet mimics the biochemical changes associated with starvation, which create ketosis. Although less commonly used in later decades because of the increased availability of anticonvulsants, the ketogenic diet has re-emerged as a therapeutic option. Only a decade ago the ketogenic diet was seen as a last resort; however, it has become more commonly used in academic centres throughout the world even early in the course of epilepsy. The Atkins diet is a recently used, less restrictive, therapy that also creates ketosis and can lower the number of seizures. Dietary therapies may become even more valuable in the therapy of epilepsy when the mechanisms underlying their success are understood.
UR - http://www.scopus.com/inward/record.url?scp=2942702105&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2942702105&partnerID=8YFLogxK
U2 - 10.1016/S1474-4422(04)00807-5
DO - 10.1016/S1474-4422(04)00807-5
M3 - Review article
C2 - 15207798
AN - SCOPUS:2942702105
SN - 1474-4422
VL - 3
SP - 415
EP - 420
JO - Lancet Neurology
JF - Lancet Neurology
IS - 7
ER -